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The art of blocking ADP-ribosyltransferases (ARTs): nanobodies as experimental and therapeutic tools to block mammalian and toxin ARTsSingle domain antibodies: promising experimental and therapeutic tools in infection and immunityDNA-Encoded Flagellin Activates Toll-Like Receptor 5 (TLR5), Nod-like Receptor Family CARD Domain-Containing Protein 4 (NRLC4), and Acts as an Epidermal, Systemic, and Mucosal-AdjuvantValidation of nanobody and antibody based in vivo tumor xenograft NIRF-imaging experiments in mice using ex vivo flow cytometry and microscopy.A recombinant heavy chain antibody approach blocks ART2 mediated deletion of an iNKT cell population that upon activation inhibits autoimmune diabetesIndoxyl Sulfate Affects Glial Function Increasing Oxidative Stress and Neuroinflammation in Chronic Kidney Disease: Interaction between Astrocytes and Microglia.Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2-P2X7 pathwayP2X7 on Mouse T Cells: One Channel, Many FunctionsADP-ribosylation of P2X7: a matter of life and death for regulatory T cells and natural killer T cells.Nucleotide-Induced Membrane-Proximal Proteolysis Controls the Substrate Specificity of T Cell Ecto-ADP-Ribosyltransferase ARTC2.2.Molecular imaging of tumors with nanobodies and antibodies: Timing and dosage are crucial factors for improved in vivo detection.In vivo near-infrared fluorescence targeting of T cells: comparison of nanobodies and conventional monoclonal antibodies.Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.Tuning IL-2 signaling by ADP-ribosylation of CD25.Nanobodies as modulators of inflammation: potential applications for acute brain injury.NAD+ and ATP released from injured cells induce P2X7-dependent shedding of CD62L and externalization of phosphatidylserine by murine T cells.Technical Advance: a new cell preparation strategy that greatly improves the yield of vital and functional Tregs and NKT cells.Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia.IL-23 (Interleukin-23)-Producing Conventional Dendritic Cells Control the Detrimental IL-17 (Interleukin-17) Response in Stroke.Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation.Proteomic Characterization of the Heart and Skeletal Muscle Reveals Widespread Arginine ADP-Ribosylation by the ARTC1 EctoenzymeRe-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobodyBlockade of Murine ARTC2.2 During Cell Preparation Preserves the Vitality and Function of Liver Tissue-Resident Memory T CellsP2X4 receptor controls microglia activation and favors remyelination in autoimmune encephalitisMonitoring the Sensitivity of T Cell Populations Towards NAD+ Released During Cell PreparationCurrent Approaches and Future Perspectives for Nanobodies in Stroke Diagnostic and Therapy
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P50
description
hulumtues
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հետազոտող
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Björn Rissiek
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Björn Rissiek
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Björn Rissiek
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Björn Rissiek
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Björn Rissiek
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Björn Rissiek
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Björn Rissiek
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Björn Rissiek
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Björn Rissiek
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Björn Rissiek
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Björn Rissiek
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Björn Rissiek
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Björn Rissiek
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Björn Rissiek
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Björn Rissiek
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P106
P21
P31
P496
0000-0001-5327-5479