Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani.

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Current Screening Methodologies in Drug Discovery for Selected Human Diseases

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Q57169512-B0E9FB76-11AE-44FD-A332-AEE95711BD85

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Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani.

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Chemical Validation of Methion ...... Target in Leishmania donovani.

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Chemical Validation of Methion ...... Target in Leishmania donovani.

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Chemical Validation of Methion ...... Target in Leishmania donovani.

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Chemical Validation of Methion ...... Target in Leishmania donovani.

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Chemical Validation of Methion ...... Target in Leishmania donovani.

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Chemical Validation of Methion ...... Target in Leishmania donovani.

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P1476

Chemical Validation of Methion ...... Target in Leishmania donovani.

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P2093

Andrea Nühs

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Eun Jung Ko

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Frederick R C Simeons

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Jennifer Riley

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John Thomas

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Kevin D Read

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Laste Stojanovski

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Leah S Torrie

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Lorna MacLean

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Lucy Ellis

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P2860

Membrane flow during pinocytosis. A stereologic analysis

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Structure of Leishmania major methionyl-tRNA synthetase in complex with intermediate products methionyladenylate and pyrophosphate

Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection

Structures of Trypanosoma brucei methionyl-tRNA synthetase with urea-based inhibitors provide guidance for drug design against sleeping sickness

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Development and Validation of a Novel Leishmania donovani Screening Cascade for High-Throughput Screening Using a Novel Axenic Assay with High Predictivity of Leishmanicidal Intracellular Activity.

Drug resistance in leishmaniasis

Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors

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scholarly article

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10.1021/ACSINFECDIS.7B00047

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2017-10-02T00:00:00Z

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28967262

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5663395

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Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani.

about

P2860

P2860

Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani.

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P1476

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