α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism.

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Current perspective of mitochondrial biology in Parkinson's disease.D409H GBA1 mutation accelerates the progression of pathology in A53T α-synuclein transgenic mouse model.

P2860

Q52351688-794416D5-BA4B-4C5F-9BFB-9264FDB5EC21 Q55516103-F5002303-7CF2-4063-8F1B-7D83520C733C

P2860

α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism.

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http://www.wikidata.org/entity/Q47193560

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

@zh-cn

2018年学术文章

@zh-hans

2018年学术文章

@zh-my

2018年学术文章

@zh-sg

2018年學術文章

@yue

2018年學術文章

@zh-hant

name

α-Synuclein accumulation and G ...... to MPTP-induced parkinsonism.

@en

α-Synuclein accumulation and G ...... to MPTP-induced parkinsonism.

@nl

type

Item

label

α-Synuclein accumulation and G ...... to MPTP-induced parkinsonism.

@en

α-Synuclein accumulation and G ...... to MPTP-induced parkinsonism.

@nl

prefLabel

α-Synuclein accumulation and G ...... to MPTP-induced parkinsonism.

@en

α-Synuclein accumulation and G ...... to MPTP-induced parkinsonism.

@nl

P1476

α-Synuclein accumulation and G ...... s to MPTP-induced parkinsonism

@en

P2093

Donghoon Kim

http://www.w3.org/2001/XMLSchema#string

Han Seok Ko

http://www.w3.org/2001/XMLSchema#string

Jae Hong Park

http://www.w3.org/2001/XMLSchema#string

Saebom Lee

http://www.w3.org/2001/XMLSchema#string

SangMin Kim

http://www.w3.org/2001/XMLSchema#string

Sangjune Kim

http://www.w3.org/2001/XMLSchema#string

Senthilkumar S Karuppagounder

http://www.w3.org/2001/XMLSchema#string

Seung Pil Yun

http://www.w3.org/2001/XMLSchema#string

Seung-Hwan Kwon

http://www.w3.org/2001/XMLSchema#string

Suhyun Lee

http://www.w3.org/2001/XMLSchema#string

P2860

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease

Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function

Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies

Inactivation of Pink1 gene in vivo sensitizes dopamine-producing neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and can be rescued by autosomal recessive Parkinson disease genes, Parkin or DJ-1

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Glucocerebrosidase is shaking up the synucleinopathies

Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease

Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein.

P2888

s13024-017-0233-5

P304

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scholarly article

P356

10.1186/S13024-017-0233-5

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Sangwoo Ham

Tae-In Kam

P577

2018-01-08T00:00:00Z

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P6179

1100258786

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P698

29310663

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P921

Parkinson's disease

Synuclein

P932

5759291

http://www.w3.org/2001/XMLSchema#string

α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism.

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P2860

P2860

α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism.

description

name

type

label

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P1433

P1476

P2093

P2860

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P31

P356

P433

P478

P50

P577

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P1476

P2093

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P356

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