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Residue 259 is a key determinant of substrate specificity of protein-tyrosine phosphatases 1B and alphaStructure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1BCrystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 ReceptorComputational analysis of chain flexibility and fluctuations in Rhizomucor miehei lipase.Membrane restructuring by phospholipase A2 is regulated by the presence of lipid domainsDomain-induced activation of human phospholipase A2 type IIA: local versus global lipid composition.Computational investigation of enthalpy-entropy compensation in complexation of glycoconjugated bile salts with β-cyclodextrin and analogs.The effect of Asp54 phosphorylation on the energetics and dynamics in the response regulator protein Spo0F studied by molecular dynamics.Drug delivery by an enzyme-mediated cyclization of a lipid prodrug with unique bilayer-formation properties.Synthesis and serotonin transporter activity of sulphur-substituted alpha-alkyl phenethylamines as a new class of anticancer agents.Methyl 1-ethyl-3'-[hy-droxy(naphthalen-1-yl)meth-yl]-1'-methyl-2-oxo-spiro-[indo-line-3,2'-pyrrolidine]-3'-carboxyl-ateCorrelated volume-energy fluctuations of phospholipid membranes: a simulation studySimulations of a membrane-anchored peptide: structure, dynamics, and influence on bilayer properties.Reconciliation of opposing views on membrane-sugar interactions.Essential motions in a fungal lipase with bound substrate, covalently attached inhibitor and product.Ammonium recruitment and ammonia transport by E. coli ammonia channel AmtBSimulation of the coupling between nucleotide binding and transmembrane domains in the ATP binding cassette transporter BtuCD.Reparameterization of all-atom dipalmitoylphosphatidylcholine lipid parameters enables simulation of fluid bilayers at zero tension.The Importance of Magnesium in the Human Body: A Systematic Literature Review.Synthesis and serotonin transporter activity of 1,3-bis(aryl)-2-nitro-1-propenes as a new class of anticancer agents.Mechanistic study of the sPLA2-mediated hydrolysis of a thio-ester pro anticancer ether lipid.Oligomerization of a Glucagon-like Peptide 1 Analog: Bridging Experiment and Simulations.A novel strategy for the development of selective active-site inhibitors of the protein tyrosine phosphatase-like proteins islet-cell antigen 512 (IA-2) and phogrin (IA-2beta).Membrane Interaction of the Factor VIIIa Discoidin Domains in Atomistic Detail.Stabilization of tryptophan hydroxylase 2 by l-phenylalanine-induced dimerization.Residue 182 influences the second step of protein-tyrosine phosphatase-mediated catalysis.Electrostatic evaluation of the signature motif (H/V)CX5R(S/T) in protein-tyrosine phosphatases.Secretory phospholipase A2 activity toward diverse substrates.Binding of serotonin to lipid membranes.Residue 259 in protein-tyrosine phosphatase PTP1B and PTPalpha determines the flexibility of glutamine 262.Affinity of four polar neurotransmitters for lipid bilayer membranes.Development of a cysteine-deprived and C-terminally truncated GLP-1 receptor.Proof of the identity between the depletion layer thickness and half the average span for an arbitrary polymer chain.Equilibrium partitioning of macromolecules in confining geometries: improved universality with a new molecular size parameter.Isoform-Specific Substrate Inhibition Mechanism of Human Tryptophan Hydroxylase.The influence of different linker modifications on the catalytic activity and cellulose affinity of cellobiohydrolase Cel7A from Hypocrea jecorina.Glucagon-like Peptide 1 Conjugated to Recombinant Human Serum Albumin Variants with Modified Neonatal Fc Receptor Binding Properties. Impact on Molecular Structure and Half-Life.Dual Nicotinic Acetylcholine Receptors α4β2 Antagonists/α7 Agonists: Synthesis, Docking Studies and Pharmacological Evaluation of Tetrahydroisoquinolines and Tetrahydroisoquinolinium Salts.Molecular packing in 1-hexanol-DMPC bilayers studied by molecular dynamics simulation.Chemoenzymatic synthesis of fluorogenic phospholipids and evaluation in assays of phospholipases A, C and D.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Günther H Peters
@ast
Günther H Peters
@en
Günther H Peters
@es
Günther H Peters
@nl
Günther H Peters
@sl
type
label
Günther H Peters
@ast
Günther H Peters
@en
Günther H Peters
@es
Günther H Peters
@nl
Günther H Peters
@sl
prefLabel
Günther H Peters
@ast
Günther H Peters
@en
Günther H Peters
@es
Günther H Peters
@nl
Günther H Peters
@sl
P1053
T-7100-2017
P106
P21
P31
P3829
P496
0000-0001-9754-2663