A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.

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Elongator subunit 3 (ELP3) modifies ALS through tRNA modification.Expression of C9orf72-related dipeptides impairs motor function in a vertebrate model.

P2860

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A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.

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http://www.wikidata.org/entity/Q47230701

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.

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A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.

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label

A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.

@en

A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.

@nl

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A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.

@en

A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.

@nl

P1476

A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism

@en

P2093

Adrian M Isaacs

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Andre Bento-Abreu

http://www.w3.org/2001/XMLSchema#string

Elke Bogaert

http://www.w3.org/2001/XMLSchema#string

Jiou Wang

http://www.w3.org/2001/XMLSchema#string

Leonard Petrucelli

http://www.w3.org/2001/XMLSchema#string

Mieke Timmers

http://www.w3.org/2001/XMLSchema#string

Nicole Hersmus

http://www.w3.org/2001/XMLSchema#string

Philip Van Damme

http://www.w3.org/2001/XMLSchema#string

Rik Nuyts

http://www.w3.org/2001/XMLSchema#string

Robin Lemmens

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P2860

RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS

State of play in amyotrophic lateral sclerosis genetics

Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration

Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons

C9orf72 nucleotide repeat structures initiate molecular cascades of disease.

Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy

Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions

Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration

P2888

s00401-017-1796-5

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427-443

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scholarly article

P356

10.1007/S00401-017-1796-5

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P433

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P478

135

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Ludo Van Den Bosch

Sarah Mizielinska

Bart Swinnen

P577

2018-01-04T00:00:00Z

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P698

29302778

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P921

amyotrophic lateral sclerosis

A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.

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P2860

P2860

A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.

description

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type

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P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P433

P478

P50

P577

P698

P921

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P433

P478

P50

P577

P698

P921