about
The therapeutic potential of metal-based antimalarial agents: implications for the mechanism of actionFerrocene-based antimalarialsAssessment of Plasmodium falciparum resistance to ferroquine (SSR97193) in field isolates and in W2 strain under pressure.α-L-fucosidase inhibition by pyrrolidine-ferrocene hybrids: rationalization of ligand-binding properties by structural studiesCiprofloxacin Derivatives Affect Parasite Cell Division and Increase the Survival of Mice Infected with Toxoplasma gondiiDevelopment of novel statistical potentials describing cation-pi interactions in proteins and comparison with semiempirical and quantum chemistry approaches.Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach.The antimalarial ferroquine: from bench to clinic.What is paradoxical about Levinthal paradox?Plasmodium falciparum apicoplast drugs: targets or off-targets?4-Aminoquinoline-β-lactam conjugates: synthesis, antimalarial, and antitubercular evaluation.Assessing ER and Golgi N-glycosylation process using metabolic labeling in mammalian cultured cells.A new piperidinol derivative targeting mycolic acid transport in Mycobacterium abscessus.Pharmacokinetics of ferroquine, a novel 4-aminoquinoline, in asymptomatic carriers of Plasmodium falciparum infections.Ferrocene conjugates of chloroquine and other antimalarials: the development of ferroquine, a new antimalarial.Organometallic complexes: new tools for chemotherapy.Medicinal potential of ciprofloxacin and its derivatives.New heterocyclic compounds: Synthesis and antitrypanosomal properties.The antimalarial ferroquine is an inhibitor of hepatitis C virus.Iminosugar-ferrocene conjugates as potential anticancer agents.Platinum(II) and palladium(II) complexes with (N,N') and (C,N,N')- ligands derived from pyrazole as anticancer and antimalarial agents: synthesis, characterization and in vitro activities.Structural analysis of an unusual bioactive N-acylated lipo-oligosaccharide LOS-IV in Mycobacterium marinum.Antimalarial versus cytotoxic properties of dual drugs derived from 4-aminoquinolines and Mannich bases: interaction with DNA.Deciphering the Resistance-Counteracting Functions of Ferroquine in Plasmodium falciparum-Infected Erythrocytes.Synthesis and in vitro antitubercular activity of ferrocene-based hydrazones.5-substituted tetrazoles as bioisosteres of carboxylic acids. Bioisosterism and mechanistic studies on glutathione reductase inhibitors as antimalarials.Double-drug development against antioxidant enzymes from Plasmodium falciparum.A prodrug form of a Plasmodium falciparum glutathione reductase inhibitor conjugated with a 4-anilinoquinoline.Probing the CMP-Sialic Acid Donor Specificity of Two Human β-d-Galactoside Sialyltransferases (ST3Gal I and ST6Gal I) Selectively Acting on O- and N-Glycosylproteins.BLISS: Shining a light on lignification in plants.Insights into the mechanism of action of ferroquine. Relationship between physicochemical properties and antiplasmodial activity.Synthesis of ferroquine enantiomers: first investigation of effects of metallocenic chirality upon antimalarial activity and cytotoxicity.Ferroquine as an oxidative shock antimalarial.Synthetic ferrocenic mefloquine and quinine analoguesas potential antimalarial agents.The ferroquine antimalarial conundrum: redox activation and reinvasion inhibition.Synthesis and antimalarial activity in vitro and in vivo of a new ferrocene-chloroquine analogue.Opening up the advantages of the ruthenocenic bioprobes of ferroquine: distribution and localization in Plasmodium falciparum-infected erythrocytes.The antimalarial ferroquine: role of the metal and intramolecular hydrogen bond in activity and resistance.Antimalarial activities of ferroquine conjugates with either glutathione reductase inhibitors or glutathione depletors via a hydrolyzable amide linker.Investigation of the redox behavior of ferroquine, a new antimalarial.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Christophe Biot
@ast
Christophe Biot
@en
Christophe Biot
@es
Christophe Biot
@fr
Christophe Biot
@nl
Christophe Biot
@sl
type
label
Christophe Biot
@ast
Christophe Biot
@en
Christophe Biot
@es
Christophe Biot
@fr
Christophe Biot
@nl
Christophe Biot
@sl
prefLabel
Christophe Biot
@ast
Christophe Biot
@en
Christophe Biot
@es
Christophe Biot
@fr
Christophe Biot
@nl
Christophe Biot
@sl
P106
P1153
6603688091
P21
P31
P496
0000-0002-7396-1959