Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons.

Item

http://www.wikidata.org/entity/Q47611066

description

2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

@wuu

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh

2017年學術文章

@zh-hant

name

Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons.

@en

Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons.

@nl

type

Item

label

Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons.

@en

Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons.

@nl

prefLabel

Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons.

@en

Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons.

@nl

P1476

Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons.

@en

P2093

Allison D Ebert

http://www.w3.org/2001/XMLSchema#string

Andrew J Schwab

http://www.w3.org/2001/XMLSchema#string

John A Corbett

http://www.w3.org/2001/XMLSchema#string

Katarzyna A Broniowska

http://www.w3.org/2001/XMLSchema#string

Michael R Meade

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Samantha L Sison

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P2860

Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.

Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors.

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

The familial Parkinsonism gene LRRK2 regulates neurite process morphology

G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization

Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

P304

1839-1852

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P31

scholarly article

P356

10.1016/J.STEMCR.2017.10.010

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P433

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P478

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P577

2017-10-31T00:00:00Z

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P698

29129681

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P921

dopamine

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5785678

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