The PAF complex regulation of Prmt5 facilitates the progression and maintenance of MLL fusion leukemia.

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PAF1 complex interactions with SETDB1 mediate promoter H3K9 methylation and transcriptional repression of Hoxa9 and Meis1 in acute myeloid leukemia.

P2860

Q55039489-62000F85-9E98-4E1C-B107-856FAC4193B2

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The PAF complex regulation of Prmt5 facilitates the progression and maintenance of MLL fusion leukemia.

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http://www.wikidata.org/entity/Q47748522

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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2017年學術文章

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name

The PAF complex regulation of ...... enance of MLL fusion leukemia.

@en

The PAF complex regulation of ...... enance of MLL fusion leukemia.

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type

Item

label

The PAF complex regulation of ...... enance of MLL fusion leukemia.

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The PAF complex regulation of ...... enance of MLL fusion leukemia.

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prefLabel

The PAF complex regulation of ...... enance of MLL fusion leukemia.

@en

The PAF complex regulation of ...... enance of MLL fusion leukemia.

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P1476

The PAF complex regulation of ...... enance of MLL fusion leukemia.

@en

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A G Muntean

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J Grembecka

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J Ropa

http://www.w3.org/2001/XMLSchema#string

J Serio

http://www.w3.org/2001/XMLSchema#string

J Wang

http://www.w3.org/2001/XMLSchema#string

L Chen

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M Mysliwski

http://www.w3.org/2001/XMLSchema#string

N Saha

http://www.w3.org/2001/XMLSchema#string

T Cierpicki

http://www.w3.org/2001/XMLSchema#string

W Chen

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P2860

Human RNA polymerase II-association factor 1 (hPaf1/PD2) regulates histone methylation and chromatin remodeling in pancreatic cancer

The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS

HOXA9 methylation by PRMT5 is essential for endothelial cell expression of leukocyte adhesion molecules

The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis

CARM1 methylates chromatin remodeling factor BAF155 to enhance tumor progression and metastasis

RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells

Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II

Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes

Identification and characterization of Hoxa9 binding sites in hematopoietic cells

Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance

P2888

onc.2017.337

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450-460

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scholarly article

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10.1038/ONC.2017.337

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English

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P478

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Haixing Miao

P577

2017-09-25T00:00:00Z

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28945229

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P932

5785415

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The PAF complex regulation of Prmt5 facilitates the progression and maintenance of MLL fusion leukemia.

about

P2860

P2860

The PAF complex regulation of Prmt5 facilitates the progression and maintenance of MLL fusion leukemia.

description

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type

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P1433

P1476

P2093

P2860

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P31

P356

P407

P433

P478

P50

P577

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P932

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932