about
Type II antithrombin deficiency caused by a large in-frame insertion: structural, functional and pathological relevanceIncreased N-glycosylation efficiency by generation of an aromatic sequon on N135 of antithrombinProduction of the apoptotic cellular mediator 4-Methylthio-2-oxobutyric acid by using an enzymatic stirred tank reactor with in situ product removal.Implication of a mutation in the flavin binding site on the specific activity and substrate specificity of glycine oxidase from Bacillus subtilis produced by directed evolution.An atypical IgM class platelet cold agglutinin induces GPVI-dependent aggregation of human platelets.GPI-anchor and GPI-anchored protein expression in PMM2-CDG patients.Potential role of miRNAs in developmental haemostasisAntithrombin Murcia (K241E) causing antithrombin deficiency: a possible role for altered glycosylation.Amelioration of the severity of heparin-binding antithrombin mutations by posttranslational mosaicism.Identification of antithrombin-modulating genes. Role of LARGE, a gene encoding a bifunctional glycosyltransferase, in the secretion of proteins?Role of the C-sheet in the maturation of N-glycans on antithrombin: functional relevance of pleiotropic mutations.Heparanase Activates Antithrombin through the Binding to Its Heparin Binding SiteControl of post-translational modifications in antithrombin during murine post-natal development by miR-200aFunctional consequences of the prothrombotic SERPINC1 rs2227589 polymorphism on antithrombin levelsIdentification of miRNAs as potential modulators of tissue factor expression in patients with systemic lupus erythematosus and antiphospholipid syndrome.Heparin affinity of factor VIIa: implications on the physiological inhibition by antithrombin and clearance of recombinant factor VIIa.Hypoglycosylation is a common finding in antithrombin deficiency in the absence of a SERPINC1 gene defect.Antithrombin controls tumor migration, invasion and angiogenesis by inhibition of enteropeptidase.Characterization of a novel thermostable carboxylesterase from Geobacillus kaustophilus HTA426 shows the existence of a new carboxylesterase family.Characterization of a new rhamnogalacturonan acetyl esterase from Bacillus halodurans C-125 with a new putative carbohydrate binding domain.Severe Thrombophilia in Idiopathic Fatal Pulmonary Embolism.Disease-causing mutations in the serpin antithrombin reveal a key domain critical for inhibiting protease activities.S-adenosylhomocysteine hydrolase from Corynebacterium glutamicum: cloning, overexpression, purification, and biochemical characterization.Maximization of production of his-tagged glycine oxidase and its M261 mutant proteins.YesT: a new rhamnogalacturonan acetyl esterase from Bacillus subtilis.Effect of citrullination on the function and conformation of antithrombin.Effects of acrolein, a natural occurring aldehyde, on the anticoagulant serpin antithrombin.Hyperglycaemia impairs antithrombin secretion: possible contribution to the thrombotic risk of diabetes.Dexamethasone induces a heat-stress response that ameliorates the conformational consequences on antithrombin of L-asparaginase treatment.Cloning, overexpression, purification, and characterization of S-adenosylhomocysteine hydrolase from Corynebacterium efficiens YS-314.A colorimetric assay for S-adenosylhomocysteine hydrolase.Characterization and structural modeling of a novel thermostable glycine oxidase from Geobacillus kaustophilus HTA426.Identification of potential oviductal factors responsible for zona pellucida hardening and monospermy during fertilization in mammals.Rare homozygous status of P43 β1-tubulin polymorphism causes alterations in platelet ultrastructure.A colorimetric assay for the determination of acetyl xylan esterase or cephalosporin C acetyl esterase activities using 7-amino cephalosporanic acid, cephalosporin C, or acetylated xylan as substrate.High-level production of bacillus subtilis glycine oxidase by fed-batch cultivation of recombinant Escherichia coli Rosetta (DE3).Antithrombin Dublin (p.Val30Glu): a relatively common variant with moderate thrombosis risk of causing transient antithrombin deficiency.Congenital disorder of glycosylation (PMM2-CDG) in a patient with antithrombin deficiency and severe thrombophilia.In Silico Discovery of a Compound with Nanomolar Affinity to Antithrombin Causing Partial Activation and Increased Heparin AffinityA new method to quantify β-antithrombin glycoform in plasma reveals increased levels during the acute stroke event
P50
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Irene Martínez-Martínez
@ast
Irene Martínez-Martínez
@en
Irene Martínez-Martínez
@es
Irene Martínez-Martínez
@nl
Irene Martínez-Martínez
@sl
type
label
Irene Martínez-Martínez
@ast
Irene Martínez-Martínez
@en
Irene Martínez-Martínez
@es
Irene Martínez-Martínez
@nl
Irene Martínez-Martínez
@sl
prefLabel
Irene Martínez-Martínez
@ast
Irene Martínez-Martínez
@en
Irene Martínez-Martínez
@es
Irene Martínez-Martínez
@nl
Irene Martínez-Martínez
@sl
P106
P1153
14012015600
P21
P31
P496
0000-0002-1067-6464