High-throughput sequencing of DNA G-quadruplex structures in the human genome.
about
G-quadruplexes and helicasesThe exception that confirms the rule: a higher-order telomeric G-quadruplex structure more stable in sodium than in potassium.G-Quadruplexes Involving Both Strands of Genomic DNA Are Highly Abundant and Colocalize with Functional Sites in the Human GenomeRe-evaluation of G-quadruplex propensity with G4HunterG-quadruplexes with (4n - 1) guanines in the G-tetrad core: formation of a G-triad·water complex and implication for small-molecule bindingSelective Luminescent Labeling of DNA and RNA Quadruplexes by π-Extended Ruthenium Light-Up Probes.Specific targeting of telomeric multimeric G-quadruplexes by a new triaryl-substituted imidazole.PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA.Cancer-associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expressionTetrahelical structural family adopted by AGCGA-rich regulatory DNA regions.Targeting glioma stem cells in vivo by a G-quadruplex-stabilizing synthetic macrocyclic hexaoxazole.Small Molecule Microarrays Enable the Identification of a Selective, Quadruplex-Binding Inhibitor of MYC Expression.GNG Motifs Can Replace a GGG Stretch during G-Quadruplex Formation in a Context Dependent MannerDiscovery of a Family of Genomic Sequences Which Interact Specifically with the c-MYC Promoter to Regulate c-MYC Expression.Computational Analysis of G-Quadruplex Forming Sequences across Chromosomes Reveals High Density Patterns Near the Terminal Ends.Structural Analysis of G-Quadruplex Formation at the Human MEST Promoter.Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds.Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevanceReplicating Large Genomes: Divide and Conquer.Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage.G-quadruplex and G-rich sequence stimulate Pif1p-catalyzed downstream duplex DNA unwinding through reducing waiting time at ss/dsDNA junction.G-quadruplex recognition and remodeling by the FANCJ helicasePutative RNA-Directed Adaptive Mutations in Cancer Evolution.CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumoursRNA G-quadruplexes are globally unfolded in eukaryotic cells and depleted in bacteria.Guanine quadruplex monoclonal antibody 1H6 cross-reacts with restrained thymidine-rich single stranded DNA.High-resolution three-dimensional NMR structure of the KRAS proto-oncogene promoter reveals key features of a G-quadruplex involved in transcriptional regulation.Template-Mediated Stabilization of a DNA G-Quadruplex formed in the HIV-1 Promoter and Comparative Binding Studies.Altered biochemical specificity of G-quadruplexes with mutated tetrads.Templated Formation of Discrete RNA and DNA:RNA Hybrid G-Quadruplexes and Their Interactions with Targeting Ligands.AID Recognizes Structured DNA for Class Switch Recombination.G-quadruplex structures mark human regulatory chromatin.RNA G-quadruplexes: emerging mechanisms in diseaseA practical guide to studying G-quadruplex structures using single-molecule FRET.Mechanistic and biological considerations of oxidatively damaged DNA for helicase-dependent pathways of nucleic acid metabolism.The functions of the multi-tasking Pfh1Pif1 helicase.RNA G-quadruplexes and their potential regulatory roles in translation.A direct view of the complex multi-pathway folding of telomeric G-quadruplexes.On the binding modes of metal NHC complexes with DNA secondary structures: implications for therapy and imaging.DSBCapture: in situ capture and sequencing of DNA breaks.
P2860
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P2860
High-throughput sequencing of DNA G-quadruplex structures in the human genome.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
High-throughput sequencing of DNA G-quadruplex structures in the human genome.
@en
High-throughput sequencing of DNA G-quadruplex structures in the human genome.
@nl
type
label
High-throughput sequencing of DNA G-quadruplex structures in the human genome.
@en
High-throughput sequencing of DNA G-quadruplex structures in the human genome.
@nl
prefLabel
High-throughput sequencing of DNA G-quadruplex structures in the human genome.
@en
High-throughput sequencing of DNA G-quadruplex structures in the human genome.
@nl
P2093
P2860
P50
P356
P1433
P1476
High-throughput sequencing of DNA G-quadruplex structures in the human genome.
@en
P2093
Geoffrey P Smith
Giovanni Marsico
Jonathan M Boutell
P2860
P2888
P304
P356
10.1038/NBT.3295
P577
2015-07-20T00:00:00Z