Rhizoxin binding to tubulin at the maytansine-binding site.
about
Identification of a novel topoisomerase inhibitor effective in cells overexpressing drug efflux transportersPhase II clinical trials with rhizoxin in breast cancer and melanoma. The EORTC Early Clinical Trials Group.Preparative isolation and purification of anti-tumor agent ansamitocin P-3 from fermentation broth of Actinosynnema pretiosum using high-performance counter-current chromatography.A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugsA previously undescribed tubulin binderDrugs that target dynamic microtubules: a new molecular perspectivePhase II trials of rhizoxin in advanced ovarian, colorectal and renal cancer.Phase II study of rhizoxin in squamous cell head and neck cancer. The EORTC Early Clinical Trials Group.Biosynthesis of polyketides by trans-AT polyketide synthases.Biosynthesis of polyketides by trans-AT polyketide synthases.Ansamitocin P3 depolymerizes microtubules and induces apoptosis by binding to tubulin at the vinblastine siteNatural Compounds as Modulators of Cell Cycle Arrest: Application for Anticancer Chemotherapies.Antiproliferative effects of ester- and amide-functionalized rhizoxin derivatives.Antimitotic agents: chemistry and recognition of tubulin molecule.Twofold polyketide branching by a stereoselective enzymatic Michael addition.Enzymatic polyketide chain branching to give substituted lactone, lactam, and glutarimide heterocycles.Contribution of serum lipoproteins as carriers of antitumour agent RS-1541 (palmitoyl rhizoxin) in mice.Tryprostatin A, a specific and novel inhibitor of microtubule assemblyEvolution of host resistance in a toxin-producing bacterial-fungal alliance.Tubulin as a target for anticancer drugs: agents which interact with the mitotic spindle.Dissociation of tubulin assembly-inhibiting and aggregation-promoting activities by a vinblastine derivative.Mechanism of action cryptophycin. Interaction with the Vinca alkaloid domain of tubulin.Characterization of the interaction of TZT-1027, a potent antitumor agent, with tubulin.A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin.
P2860
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P2860
Rhizoxin binding to tubulin at the maytansine-binding site.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
1987年學術文章
@zh
1987年學術文章
@zh-hant
name
Rhizoxin binding to tubulin at the maytansine-binding site.
@en
Rhizoxin binding to tubulin at the maytansine-binding site.
@nl
type
label
Rhizoxin binding to tubulin at the maytansine-binding site.
@en
Rhizoxin binding to tubulin at the maytansine-binding site.
@nl
prefLabel
Rhizoxin binding to tubulin at the maytansine-binding site.
@en
Rhizoxin binding to tubulin at the maytansine-binding site.
@nl
P2093
P1476
Rhizoxin binding to tubulin at the maytansine-binding site.
@en
P2093
P304
P356
10.1016/0304-4165(87)90206-6
P577
1987-12-01T00:00:00Z