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Extreme evolutionary disparities seen in positive selection across seven complex diseasesAn Environment-Wide Association Study (EWAS) on type 2 diabetes mellitusPhased whole-genome genetic risk in a family quartet using a major allele reference sequenceTranslational bioinformatics applications in genome medicineSequencing and analysis of a South Asian-Indian personal genomeOntology-driven indexing of public datasets for translational bioinformaticsAchieving high-sensitivity for clinical applications using augmented exome sequencingSystematic evaluation of environmental factors: persistent pollutants and nutrients correlated with serum lipid levelsData-driven integration of epidemiological and toxicological data to select candidate interacting genes and environmental factors in association with diseaseSystematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitusProtein microarrays discover angiotensinogen and PRKRIP1 as novel targets for autoantibodies in chronic renal diseaseClinical assessment incorporating a personal genomeCurrent methodologies for translational bioinformaticsExpression of complement components differs between kidney allografts from living and deceased donorsFoxO3 regulates neural stem cell homeostasisFinding disease-related genomic experiments within an international repository: first steps in translational bioinformaticsCoordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1Quantifying the relationship between co-expression, co-regulation and gene functionReproducibility of gene expression across generations of Affymetrix microarraysSystematic survey reveals general applicability of "guilt-by-association" within gene coexpression networksTranslational bioinformatics in the cloud: an affordable alternativeWhole-exome sequencing reveals TopBP1 as a novel gene in idiopathic pulmonary arterial hypertensionTranslational bioinformatics: linking knowledge across biological and clinical realmsNetwork-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targetsFoxO6 regulates memory consolidation and synaptic functionDO CANCER CLINICAL TRIAL POPULATIONS TRULY REPRESENT CANCER PATIENTS? A COMPARISON OF OPEN CLINICAL TRIALS TO THE CANCER GENOME ATLASA survey of current trends in computational drug repositioningOpening clinical trial data: are the voluntary data-sharing portals enough?Leveraging models of cell regulation and GWAS data in integrative network-based association studiesIn silico research in the era of cloud computingTranslational bioinformatics: coming of ageMutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum-associated degradation pathwayPersonal omics profiling reveals dynamic molecular and medical phenotypesTen years of pathway analysis: current approaches and outstanding challengesReport on EU-USA workshop: how systems biology can advance cancer research (27 October 2008)RImmPort: an R/Bioconductor package that enables ready-for-analysis immunology research data.Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease.Identification of cell surface targets through meta-analysis of microarray data.Population genetic inference from personal genome data: impact of ancestry and admixture on human genomic variation.Database integration of 4923 publicly-available samples of breast cancer molecular and clinical data.
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American medical researcher
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Amerikaans bioloog
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ahli biologi asal Amerika Serikat
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أحيائي من الولايات المتحدة الأمريكية
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زیستشناس آمریکایی
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P101
P184
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P2002
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0000-0002-7433-2740