Bin1 and CD2AP polarise the endocytic generation of beta-amyloid.
about
Untangling Genetic Risk for Alzheimer's Disease.Bin1 directly remodels actin dynamics through its BAR domain.Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A.Heterogeneous Association of Alzheimer's Disease-Linked Amyloid-β and Amyloid-β Protein Precursor with Synapses.M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memory.The physical approximation of APP and BACE-1: A key event in alzheimer's disease pathogenesis.Disruption of amyloid precursor protein ubiquitination selectively increases amyloid β (Aβ) 40 levels via presenilin 2-mediated cleavage.Amyloid precursor protein products concentrate in a subset of exosomes specifically endocytosed by neurons.Endosomal Traffic Jams Represent a Pathogenic Hub and Therapeutic Target in Alzheimer's Disease.
P2860
Q39407560-C1953376-B3B4-43BE-B21B-3055F93BE3E7Q40046724-6FC26B00-E6C5-44E7-A20F-C81F6C5E5E9FQ41506935-02EC2FBD-7AAC-4841-A0C2-63D10D55BD04Q42219931-4D975165-5B1D-4FF5-90B6-0538CCA42F74Q46956989-7A3B347D-DFB1-4187-BFB4-59BB6722C4A7Q47438354-3BF2B758-544A-4A52-AF14-CF05AE245E94Q47665801-08FB596D-021E-4680-BE7D-54DEF52D19CDQ47733091-7E80ACC1-55FB-4783-97BE-F478C625D1FCQ48091173-C2CCB3D5-CFBB-4EC0-99D5-37737434F466
P2860
Bin1 and CD2AP polarise the endocytic generation of beta-amyloid.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Bin1 and CD2AP polarise the endocytic generation of beta-amyloid.
@en
Bin1 and CD2AP polarise the endocytic generation of beta-amyloid.
@nl
type
label
Bin1 and CD2AP polarise the endocytic generation of beta-amyloid.
@en
Bin1 and CD2AP polarise the endocytic generation of beta-amyloid.
@nl
prefLabel
Bin1 and CD2AP polarise the endocytic generation of beta-amyloid.
@en
Bin1 and CD2AP polarise the endocytic generation of beta-amyloid.
@nl
P2093
P2860
P50
P356
P1433
P1476
Bin1 and CD2AP polarise the endocytic generation of beta-amyloid
@en
P2093
Cláudio Ferreira
Florent Ubelmann
Laura Salavessa
Tatiana Burrinha
P2860
P304
P356
10.15252/EMBR.201642738
P577
2016-11-28T00:00:00Z