about
T cells down-regulate macrophage TNF production by IRAK1-mediated IL-10 expression and control innate hyperinflammationOncolytic polio virotherapy of cancerMitogen-activated protein kinase-interacting kinase regulates mTOR/AKT signaling and controls the serine/arginine-rich protein kinase-responsive type 1 internal ribosome entry site-mediated translation and viral oncolysis.Autoimmunity to the alpha 3 chain of type IV collagen in glomerulonephritis is triggered by 'autoantigen complementarity'.Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNA.Recombinant oncolytic poliovirus, PVSRIPO, has potent cytotoxic and innate inflammatory effects, mediating therapy in human breast and prostate cancer xenograft models.Cytotoxic and immunogenic mechanisms of recombinant oncolytic poliovirusMNK Controls mTORC1:Substrate Association through Regulation of TELO2 Binding with mTORC1.XIAP regulation by MNK links MAPK and NFκB signaling to determine an aggressive breast cancer phenotype.Cancer immunotherapy with recombinant poliovirus induces IFN-dominant activation of dendritic cells and tumor antigen-specific CTLs.Regulation of HIF-1α during Hypoxia by DAP5-Induced Translation of PHD2.MNK inversely regulates TELO2 vs. DEPTOR to control mTORC1 signaling.
P50
Q28504567-3938B24E-7314-4783-A880-4D032CD0DE60Q34425385-5F3131FA-39C4-4192-BE63-B3CDD232A20CQ34594617-3075149F-44AE-4E66-A767-41422C292FCEQ35695000-5F35C5F4-655F-4C89-8048-3B28B6729DF0Q37546968-E74DFDB6-FF41-493B-A639-D3B8C081A866Q37694857-BF60D34D-EBB7-4B59-B71D-8B9946D1887BQ38530234-5140583B-CEF2-4DF6-AE47-797FB58ECA73Q38971703-B0D14418-5E88-407C-9D0A-504382AB9578Q47558714-29D95AC0-5DB2-4A1D-A34E-B62EB1F2B990Q48319918-69DB4ED2-11B1-4E51-A434-A722C7B3CD96Q52358485-9437049A-859F-4D2D-A485-27C53D2EEE7EQ53817111-18C8FFD8-5CF7-4E31-8F49-0391384A7C24
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
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հետազոտող
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name
Michael C Brown
@ast
Michael C Brown
@en
Michael C Brown
@es
Michael C Brown
@nl
Michael C Brown
@sl
মাইকেল সি ব্রাউন
@bn
type
label
Michael C Brown
@ast
Michael C Brown
@en
Michael C Brown
@es
Michael C Brown
@nl
Michael C Brown
@sl
মাইকেল সি ব্রাউন
@bn
prefLabel
Michael C Brown
@ast
Michael C Brown
@en
Michael C Brown
@es
Michael C Brown
@nl
Michael C Brown
@sl
মাইকেল সি ব্রাউন
@bn
P106
P108
P21
P31
P496
0000-0002-3957-1164
P569
2000-01-01T00:00:00Z