Cathepsin D-mediated proteolysis of apolipoprotein E: possible role in Alzheimer's disease.
about
The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretionsProteolytic cleavage of apolipoprotein E4 as the keystone for the heightened risk associated with Alzheimer's diseaseCathepsin D--many functions of one aspartic proteaseNeuronal gene expression in non-demented individuals with intermediate Alzheimer's Disease neuropathologyNuclear uptake of an amino-terminal fragment of apolipoprotein E4 promotes cell death and localizes within microglia of the Alzheimer's disease brain.Frontiers in the pathogenesis of Alzheimer's disease.Mass spectrometry quantification revealed accumulation of C-terminal fragment of apolipoprotein E in the Alzheimer's frontal cortex.Extracellular proteolysis of apolipoprotein E (apoE) by secreted serine neuronal proteaseMicroarray expression analysis and identification of serum biomarkers for Niemann-Pick disease, type C1.Deciphering the mechanism underlying late-onset Alzheimer disease.Progress towards a consensus on biomarkers for Alzheimer's disease: a review of peripheral analytes.The Role of Cathepsin D in the Pathogenesis of Human Neurodegenerative Disorders.Yeast as a tool to explore cathepsin D function.Ageing-induced changes in the redox status of peripheral motor nerves imply an effect on redox signalling rather than oxidative damage.Cathepsin D in Podocytes Is Important in the Pathogenesis of Proteinuria and CKD.Intracellular Cholesterol Trafficking and Impact in Neurodegeneration.Ligand-based virtual screening and molecular docking studies to identify the critical chemical features of potent cathepsin D inhibitors.Cathepsin D regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis.DmCatD, a cathepsin D-like peptidase of the hematophagous insect Dipetalogaster maxima (Hemiptera: Reduviidae): Purification, bioinformatic analyses and the significance of its interaction with lipophorin in the internalization by developing oocytesDysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease.Evaluation of Apolipoprotein E Fragmentation as a Biomarker for Alzheimer's Disease.Endogenous Apolipoprotein E (ApoE) Fragmentation Is Linked to Amyloid Pathology in Transgenic Mouse Models of Alzheimer's Disease.Association study of cathepsin D gene polymorphism in Iranian patients with sporadic late-onset Alzheimer's disease.Cathepsin D as a therapeutic target in Alzheimer's disease.Is Beta-Amyloid Accumulation a Cause or Consequence of Alzheimer's Disease?
P2860
Q24628711-13EC27FE-CB07-4119-8710-14A78AF1673CQ27011311-F34FAB57-28B7-4B5E-B04E-BB135170BD95Q28275626-0C387161-353F-4852-9423-EA5AED252214Q33345759-BA968CE5-78F6-4B39-A0F2-4B84F13EEB7DQ33700412-F1ED3636-13A5-4970-AC4A-28B9ACDCBE73Q34572020-F29AA95B-AA42-40F0-B7CE-D8D17B57FEDAQ34674992-303CA7FA-65B8-405E-8D55-8724D4EDE84AQ35133505-1F6EA13E-00BA-4D90-A3E3-6EE45C0F975FQ36122424-E03C43CC-3C4F-4E4D-90FF-60A19AD4F8A3Q38062817-DE5ECC8E-C7FD-4442-BBF9-EE38E7BE9F7AQ38125769-E3D1E6FA-4801-46E8-851A-26208D72F024Q38817664-FB6228A8-A838-428E-9AB0-302D41CB2316Q39208117-80916FF4-79F0-46EC-B6DB-02EDF261601FQ39997414-A5DBF008-3A64-4237-A59D-D4B03786FFABQ40974192-CB560FCB-97EA-4265-A3BB-8AB4B110172EQ45305840-FD3B348F-9704-4B04-B0C8-B44D41A96A5AQ46590926-D200A94B-D3E2-4811-BFA1-476C5A5E5957Q47305008-BF6EC6CF-9803-47F7-9D58-69FBAB8A73F6Q47869440-81F56725-AB5A-4832-AF8B-D4F46385222CQ49497621-78FCCD2E-17F3-4B39-AA3B-3AFF19C130B6Q50531623-0C7E8D65-9771-45E3-9D71-E42AD24F77A0Q53217399-0007B554-F3DC-45E0-A2EF-4AC9FD1C3997Q53346513-CEB649C2-D64D-4B51-9FAC-60E0C721E5F9Q53383359-7314FBF2-25D3-4ABA-B0D3-DF881CCF8A9DQ57211696-2D5B20D5-F645-4874-A48A-5DC93E091FE1
P2860
Cathepsin D-mediated proteolysis of apolipoprotein E: possible role in Alzheimer's disease.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Cathepsin D-mediated proteolys ...... e role in Alzheimer's disease.
@en
Cathepsin D-mediated proteolys ...... e role in Alzheimer's disease.
@nl
type
label
Cathepsin D-mediated proteolys ...... e role in Alzheimer's disease.
@en
Cathepsin D-mediated proteolys ...... e role in Alzheimer's disease.
@nl
prefLabel
Cathepsin D-mediated proteolys ...... e role in Alzheimer's disease.
@en
Cathepsin D-mediated proteolys ...... e role in Alzheimer's disease.
@nl
P2093
P921
P1433
P1476
Cathepsin D-mediated proteolys ...... e role in Alzheimer's disease.
@en
P2093
P304
P356
10.1016/J.NEUROSCIENCE.2006.08.019
P407
P577
2006-09-25T00:00:00Z