Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and Fmr1 knockout mice, a model of Fragile X syndrome.
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Serotonin, neural markers, and memoryThe serotonin receptor 7 and the structural plasticity of brain circuitsTargeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromesTherapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and BackTargeting the Serotonin 5-HT7 Receptor in the Search for Treatments for CNS Disorders: Rationale and Progress to DateFrom FMRP function to potential therapies for fragile X syndrome.Low-basicity 5-HT7 Receptor Agonists Synthesized Using the van Leusen Multicomponent Protocol5-HT7 receptors as modulators of neuronal excitability, synaptic transmission and plasticity: physiological role and possible implications in autism spectrum disorders.Interplay between serotonin 5-HT1A and 5-HT7 receptors in depressive disorders.Long-lasting beneficial effects of central serotonin receptor 7 stimulation in female mice modeling Rett syndromeGABAB receptor upregulates fragile X mental retardation protein expression in neuronsEffect of serotonin on paired associative stimulation-induced plasticity in the human motor cortex.Lack of serotonin reuptake during brain development alters rostral raphe-prefrontal network formation.Impaired activity-dependent neural circuit assembly and refinement in autism spectrum disorder genetic models.A blueprint for research on Shankopathies: a view from research on autism spectrum disorder.The role of serotonin in memory: interactions with neurotransmitters and downstream signaling.Serotonin dysregulation in Fragile X Syndrome: implications for treatment.LP-211, a selective 5-HT7 receptor agonist, increases novelty-preference and promotes risk-prone behavior in rats.The arylpiperazine derivatives N-(4-cyanophenylmethyl)-4-(2-diphenyl)-1-piperazinehexanamide and N-benzyl-4-(2-diphenyl)-1-piperazinehexanamide exert a long-lasting inhibition of human serotonin 5-HT7 receptor binding and cAMP signaling.Serotonin 5-HT7 receptor increases the density of dendritic spines and facilitates synaptogenesis in forebrain neurons.Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics.Pharmacological stimulation of the brain serotonin receptor 7 as a novel therapeutic approach for Rett syndrome.Novel agonists for serotonin 5-HT7 receptors reverse metabotropic glutamate receptor-mediated long-term depression in the hippocampus of wild-type and Fmr1 KO mice, a model of Fragile X Syndrome.Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice.Molecular biomarkers predictive of sertraline treatment response in young children with fragile X syndrome.The Search for an Effective Therapy to Treat Fragile X Syndrome: Dream or Reality?Towards metabolically stable 5-HT7 receptor ligands: a study on 1-arylpiperazine derivatives and related isosters.Time- and age-dependent effects of serotonin on gasping and autoresuscitation in neonatal mice.Persistent modification of forebrain networks and metabolism in rats following adolescent exposure to a 5-HT7 receptor agonist.Of Men and Mice: Modeling the Fragile X Syndrome.p38α MAPK signaling drives pharmacologically reversible brain and gastrointestinal phenotypes in the SERT Ala56 mouseHigh dose of 8-OH-DPAT decreases maximal dentate gyrus activation and facilitates granular cell plasticity in vivoActivation of Serotonin 5-HT Receptors Modulates Hippocampal Synaptic Plasticity by Stimulation of Adenylate Cyclases and Rescues Learning and Behavior in a Mouse Model of Fragile X SyndromeDeep Brain Stimulation Modified Autism-Like Deficits via the Serotonin System in a Valproic Acid-Induced Rat Model
P2860
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P2860
Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and Fmr1 knockout mice, a model of Fragile X syndrome.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
Activation of 5-HT7 serotonin ...... a model of Fragile X syndrome.
@en
Activation of 5-HT7 serotonin ...... a model of Fragile X syndrome.
@nl
type
label
Activation of 5-HT7 serotonin ...... a model of Fragile X syndrome.
@en
Activation of 5-HT7 serotonin ...... a model of Fragile X syndrome.
@nl
prefLabel
Activation of 5-HT7 serotonin ...... a model of Fragile X syndrome.
@en
Activation of 5-HT7 serotonin ...... a model of Fragile X syndrome.
@nl
P2093
P50
P1476
Activation of 5-HT7 serotonin ...... a model of Fragile X syndrome.
@en
P2093
Carmela M Bonaccorso
Chiara Trovato
Lara Costa
Lucia Ciranna
Michela Spatuzza
Simona D'Antoni
P304
P356
10.1016/J.BIOPSYCH.2012.06.008
P407
P577
2012-07-18T00:00:00Z