DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair.
about
Structures of closed and open conformations of dimeric human ATMmCSM-NA: predicting the effects of mutations on protein-nucleic acids interactions.DNA-PKcs, Allostery, and DNA Double-Strand Break Repair: Defining the Structure and Setting the Stage.XSuLT: a web server for structural annotation and representation of sequence-structure alignments.Combating mutations in genetic disease and drug resistance: understanding molecular mechanisms to guide drug design.Cryo-EM structure of the DNA-PK holoenzyme.What Combined Measurements From Structures and Imaging Tell Us About DNA Damage Responses.Cryo-EM structure of the SAGA and NuA4 coactivator subunit Tra1 at 3.7 angstrom resolutionCryo-EM structure of human DNA-PK holoenzyme.A central role for a region in the middleStructure of the transcription activator target Tra1 within the chromatin modifying complex SAGA.Cryo-EM structure of human ATR-ATRIP complex.Nonhomologous DNA End Joining for Repair of DNA Double-Strand Breaks.Structural step forward for NHEJ.3.9 Å structure of the yeast Mec1-Ddc2 complex, a homolog of human ATR-ATRIP.The role of DNA-PK in aging and energy metabolism.DNA requirements for interaction of the C-terminal region of Ku80 with the DNA-dependent protein kinase catalytic subunit (DNA-PKcs).The Pseudokinase Domain of Saccharomyces cerevisiae Tra1 Is Required for Nuclear Localization and Incorporation into the SAGA and NuA4 Complexes.Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex.Kinact: a computational approach for predicting activating missense mutations in protein kinases.The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.Dissection of DNA double-strand-break repair using novel single-molecule forcepsDNA-PK inhibition synergizes with oncolytic virus M1 by inhibiting antiviral response and potentiating DNA damage
P2860
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P2860
DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair.
description
2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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@zh-hans
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name
DNA-PKcs structure suggests an ...... NA double-strand break repair.
@en
DNA-PKcs structure suggests an ...... NA double-strand break repair.
@nl
type
label
DNA-PKcs structure suggests an ...... NA double-strand break repair.
@en
DNA-PKcs structure suggests an ...... NA double-strand break repair.
@nl
prefLabel
DNA-PKcs structure suggests an ...... NA double-strand break repair.
@en
DNA-PKcs structure suggests an ...... NA double-strand break repair.
@nl
P2860
P50
P356
P1433
P1476
DNA-PKcs structure suggests an ...... NA double-strand break repair.
@en
P2093
Bancinyane L Sibanda
P2860
P304
P356
10.1126/SCIENCE.AAK9654
P407
P577
2017-02-02T00:00:00Z