sameAs
Pancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas developmentIncreased islet apoptosis in Pdx1+/- miceThe thyroid hormone-inactivating type III deiodinase is expressed in mouse and human beta-cells and its targeted inactivation impairs insulin secretionIndependent requirement for ISL1 in formation of pancreatic mesenchyme and islet cellsMicroRNA miR-7 is preferentially expressed in endocrine cells of the developing and adult human pancreasNotch signalling controls pancreatic cell differentiationThe morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient miceSelective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreasPtf1a determines horizontal and amacrine cell fates during mouse retinal developmentInsulin-promoter-factor 1 is required for pancreas development in miceThe pancreatic beta-cell-specific transcription factor Pax-4 inhibits glucagon gene expression through Pax-6.Gene array identification of Ipf1/Pdx1-/- regulated genes in pancreatic progenitor cells.Retinoic acid promotes the generation of pancreatic endocrine progenitor cells and their further differentiation into beta-cellsPancreatic organogenesis--developmental mechanisms and implications for therapy.Developmental biology of the pancreas.Factors controlling pancreatic cell differentiation and function.Of mice and MEN1: Insulinomas in a conditional mouse knockout.Hyperinsulinemia Enhances Hepatic Expression of the Fatty Acid Transporter Cd36 and Provokes Hepatosteatosis and Hepatic Insulin Resistance.MFng is dispensable for mouse pancreas development and functionEndocrine cell clustering during human pancreas development.Pdx1 maintains β cell identity and function by repressing an α cell program.Asna1/TRC40 Controls β-Cell Function and Endoplasmic Reticulum Homeostasis by Ensuring Retrograde Transport.Phosphorylation marks IPF1/PDX1 protein for degradation by glycogen synthase kinase 3-dependent mechanisms.beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes.TAT-mediated neurogenin 3 protein transduction stimulates pancreatic endocrine differentiation in vitro.Nuclear factor-{kappa}B activity in {beta}-cells is required for glucose-stimulated insulin secretion.Distribution and characterization of helix-loop-helix enhancer-binding proteins from pancreatic beta cells and lymphocytes.The type 2 diabetes-associated gene ide is required for insulin secretion and suppression of α-synuclein levels in β-cells.The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site.Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion.Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner.IPF1/PDX1 deficiency and beta-cell dysfunction in Psammomys obesus, an animal With type 2 diabetes.Defective glucose-regulated insulin gene expression associated with PDX-1 deficiency in the Psammomys obesus model of type 2 diabetes.beta-Cell Pdx1 expression is essential for the glucoregulatory, proliferative, and cytoprotective actions of glucagon-like peptide-1.The homeodomain-interacting protein kinase 2 regulates insulin promoter factor-1/pancreatic duodenal homeobox-1 transcriptional activity.The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse.Attenuated Wnt signaling perturbs pancreatic growth but not pancreatic function.sox4b is a key player of pancreatic alpha cell differentiation in zebrafish.The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival.
P50
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P50
description
Swedish biologist
@en
Zweeds biologe
@nl
ahli biologi asal Swedia
@id
bitheolaí Sualannach
@ga
bióloga sueca
@ast
bióloga sueca
@es
svensk biolog
@sv
أحيائية سويدية
@ar
زیستشناس سوئدی
@fa
name
Helena Edlund
@ace
Helena Edlund
@ast
Helena Edlund
@ca
Helena Edlund
@da
Helena Edlund
@en
Helena Edlund
@es
Helena Edlund
@fi
Helena Edlund
@fr
Helena Edlund
@ga
Helena Edlund
@id
type
label
Helena Edlund
@ace
Helena Edlund
@ast
Helena Edlund
@ca
Helena Edlund
@da
Helena Edlund
@en
Helena Edlund
@es
Helena Edlund
@fi
Helena Edlund
@fr
Helena Edlund
@ga
Helena Edlund
@id
prefLabel
Helena Edlund
@ace
Helena Edlund
@ast
Helena Edlund
@ca
Helena Edlund
@da
Helena Edlund
@en
Helena Edlund
@es
Helena Edlund
@fi
Helena Edlund
@fr
Helena Edlund
@ga
Helena Edlund
@id
P108
P1153
7004557831
P21
P27
P31
P496
0000-0002-3553-7348
P569
1960-07-29T00:00:00Z