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Effective gene therapy in a mouse model of prion diseasesDeciphering the structure, growth and assembly of amyloid-like fibrils using high-speed atomic force microscopyBiophysical characterization of lithostathine. Evidences for a polymeric structure at physiological pH and a proteolysis mechanism leading to the formation of fibrils.PAP IB, a new member of the Reg gene family: cloning, expression, structural properties, and evolution by gene duplication.Optimized preparation of urine samples for two-dimensional electrophoresis and initial application to patient samples.Photoperiodic regime influences onset of lens opacities in a non-human primateDistinct transcriptome expression of the temporal cortex of the primate Microcebus murinus during brain aging versus Alzheimer's disease-like pathology.Combined measurement of PEDF, haptoglobin and tau in cerebrospinal fluid improves the diagnostic discrimination between alzheimer's disease and other dementias.The three-panel runway maze adapted to Microcebus murinus reveals age-related differences in memory and perseverance performancesAmyloid beta immunization worsens iron deposits in the choroid plexus and cerebral microbleeds.Distribution of lithostathine in the mouse lemur brain with aging and Alzheimer's-like pathology.Lessons from the analysis of nonhuman primates for understanding human aging and neurodegenerative diseasesDevelopmental determinants in non-communicable chronic diseases and ageing.Preparation and characterization of yeast nuclear extracts for efficient RNA polymerase B (II)-dependent transcription in vitro.Age effect on olfactory discrimination in a non-human primate, Microcebus murinusCoagulation factor X mediates adenovirus type 5 liver gene transfer in non-human primates (Microcebus murinus)Corrective GUSB transfer to the canine mucopolysaccharidosis VII cornea using a helper-dependent canine adenovirus vector.A Fluorescent Oligothiophene-Bis-Triazine ligand interacts with PrP fibrils and detects SDS-resistant oligomers in human prion diseases.The grey mouse lemur: a non-human primate model for ageing studies.Intraocular pressure in the smallest primate aging model: the gray mouse lemur.Thick collagen-based 3D matrices including growth factors to induce neurite outgrowth.Oligomeric-induced activity by thienyl pyrimidine compounds traps prion infectivity.Microcebus murinus retina: a new model to assess prion-related neurotoxicity in primates.Optimized overproduction, purification, characterization and high-pressure sensitivity of the prion protein in the native (PrP(C)-like) or amyloid (PrP(Sc)-like) conformation.Specific binding of dehydroepiandrosterone to the N terminus of the microtubule-associated protein MAP2.Artificial neural networks for assessing the risk of urinary calcium stone among men.Reversible protein precipitation to ensure stability during encapsulation within PLGA microspheres.CXCR7 Receptor Controls the Maintenance of Subpial Positioning of Cajal-Retzius Cells.[The diversity of aging models].Artificial neural networks for assessing the risk factors for urinary calcium stones according to gender and family history of stone.Odor discrimination assessment with an automated olfactometric method in a prosimian primate, Microcebus murinus.Carcinogen-induced mutation spectrum in wild-type, uvrA and umuC strains of Escherichia coli. Strain specificity and mutation-prone sequences.Exogenous LRRK2G2019S induces parkinsonian-like pathology in a nonhuman primatePancreatic lithostathine as a calcite habit modifierCalcium carbonate crystals promote calcium oxalate crystallization by heterogeneous or epitaxial nucleation: possible involvement in the control of urinary lithogenesisCrystallization and preliminary crystallographic study of human lithostathineLe site de référence du Partenariat européen d’innovation pour un vieillissement actif et en bonne santé MACVIA-LR (contre les maladies chroniques pour un vieillissement en bonne santé en Languedoc-Roussillon)Regenerating islet-derived 1α (REG-1α) protein increases tau phosphorylation in cell and animal models of tauopathiesAnalysis of the soluble organic matrix of five morphologically different kidney stones. Evidence for a specific role of albumin in the constitution of the stone protein matrixNucleation of calcium oxalate crystals by albumin: involvement in the prevention of stone formation
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P50
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Jean-Michel Verdier
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Jean-Michel Verdier
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Jean-Michel Verdier
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Jean-Michel Verdier
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Jean-Michel Verdier
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Jean-Michel Verdier
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Jean-Michel Verdier
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Jean-Michel Verdier
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Jean-Michel Verdier
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0000 0003 7510 9273
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