Progesterone/RANKL is a major regulatory axis in the human breast.
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Progestin effects on cell proliferation pathways in the postmenopausal mammary glandSteroid hormones, steroid receptors, and breast cancer stem cellsProgesterone and Overlooked Endocrine Pathways in Breast Cancer PathogenesisForm and function: how estrogen and progesterone regulate the mammary epithelial hierarchyThe mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapesWhere Do Bone-Targeted Agents RANK in Breast Cancer Treatment?Targeting RANKL in metastasisThe Roles of Epithelial-to-Mesenchymal Transition (EMT) and Mesenchymal-to-Epithelial Transition (MET) in Breast Cancer Bone Metastasis: Potential Targets for Prevention and TreatmentMolecular determinants of context-dependent progesterone receptor action in breast cancerGrowth of human breast tissues from patient cells in 3D hydrogel scaffoldsELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor CellsDeciphering the divergent roles of progestogens in breast cancer.Posttranslationally modified progesterone receptors direct ligand-specific expression of breast cancer stem cell-associated gene programsMinireview: Progesterone Regulation of Proliferation in the Normal Human Breast and in Breast Cancer: A Tale of Two Scenarios?BRCA1 haploinsufficiency cell-autonomously activates RANKL expression and generates denosumab-responsive breast cancer-initiating cells.Aldehyde dehydrogenase and estrogen receptor define a hierarchy of cellular differentiation in the normal human mammary epithelium.Cyclin A2 and its associated kinase activity are required for optimal induction of progesterone receptor target genes in breast cancer cellsBiology of the RANKL-RANK-OPG System in Immunity, Bone, and Beyond.Tracking progesterone receptor-mediated actions in breast cancerHuman breast progenitor cell numbers are regulated by WNT and TBX3.Dissecting the Biology of Menstrual Cycle-Associated Breast Cancer Risk.A role for site-specific phosphorylation of mouse progesterone receptor at serine 191 in vivo.Progesterone action in breast, uterine, and ovarian cancers.An ex vivo model to study hormone action in the human breast.Progesterone and Wnt4 control mammary stem cells via myoepithelial crosstalkProgesterone downregulation of miR-141 contributes to expansion of stem-like breast cancer cells through maintenance of progesterone receptor and Stat5a.Cervical (pre)neoplastic microenvironment promotes the emergence of tolerogenic dendritic cells via RANKL secretion.Effects of Combination of Estradiol with Selective Progesterone Receptor Modulators (SPRMs) on Human Breast Cancer Cells In Vitro and In Vivo.Quantification of regenerative potential in primary human mammary epithelial cells.RANK Signaling Amplifies WNT-Responsive Mammary Progenitors through R-SPONDIN1.Cripto-1 ablation disrupts alveolar development in the mouse mammary gland through a progesterone receptor-mediated pathway.Osteoprotegerin and breast cancer risk by hormone receptor subtype: a nested case-control study in the EPIC cohort.Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture.A Common Docking Domain in Progesterone Receptor-B links DUSP6 and CK2 signaling to proliferative transcriptional programs in breast cancer cellsGenomic Biomarkers for Breast Cancer Risk.Progesterone receptor and Stat5 signaling cross talk through RANKL in mammary epithelial cells.Prevention of breast cancer by RANKL/RANK blockade.BRCA and Early Events in the Development of Serous Ovarian Cancer.The prognostic role of RANK SNP rs34945627 in breast cancer patients with bone metastases.A DNA segment spanning the mouse Tnfsf11 transcription unit and its upstream regulatory domain rescues the pleiotropic biologic phenotype of the RANKL null mouse.
P2860
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P2860
Progesterone/RANKL is a major regulatory axis in the human breast.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
Progesterone/RANKL is a major regulatory axis in the human breast.
@en
Progesterone/RANKL is a major regulatory axis in the human breast.
@nl
type
label
Progesterone/RANKL is a major regulatory axis in the human breast.
@en
Progesterone/RANKL is a major regulatory axis in the human breast.
@nl
prefLabel
Progesterone/RANKL is a major regulatory axis in the human breast.
@en
Progesterone/RANKL is a major regulatory axis in the human breast.
@nl
P2093
P2860
P50
P1476
Progesterone/RANKL is a major regulatory axis in the human breast.
@en
P2093
Ayyakkannu Ayyanan
Cathrin Brisken
Jean-Francois Delaloye
Maria Gutierrez
Maryse Fiche
Tamara Tanos
Wassim Raffoul
William Dougall
P2860
P304
P356
10.1126/SCITRANSLMED.3005654
P407
P577
2013-04-01T00:00:00Z