The molecular and mathematical basis of Waddington's epigenetic landscape: a framework for post-Darwinian biology?
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Cell patterns emerge from coupled chemical and physical fields with cell proliferation dynamics: the Arabidopsis thaliana root as a study systemNon-Darwinian dynamics in therapy-induced cancer drug resistance.Single-cell gene expression profiling and cell state dynamics: collecting data, correlating data points and connecting the dotsMetabolic control of cancer cell stemness: Lessons from iPS cellsModeling the epigenetic attractors landscape: toward a post-genomic mechanistic understanding of developmentNonequilibrium population dynamics of phenotype conversion of cancer cellsThe Comet Cometh: Evolving Developmental SystemsGenerating anatomical variation through mutations in networks - implications for evolutionA model of epigenetic evolution based on theory of open quantum systemsStochasticity in the Genotype-Phenotype Map: Implications for the Robustness and Persistence of Bet-HedgingMarkov State Models of gene regulatory networksSystematic drug perturbations on cancer cells reveal diverse exit paths from proliferative stateLifecourse health development: past, present and futureClassification of transient behaviours in a time-dependent toggle switch modelCell Sorting and Noise-Induced Cell Plasticity Coordinate to Sharpen Boundaries between Gene Expression DomainsEffects of the in vitro manipulation of stem cells: epigenetic mechanisms as mediators of induced metabolic fluctuations.Reshaping the epigenetic landscape during early flower development: induction of attractor transitions by relative differences in gene decay rates.Using ontologies to study cell transitionsAn animated landscape representation of CD4+ T-cell differentiation, variability, and plasticity: insights into the behavior of populations versus cellsFrom understanding the development landscape of the canonical fate-switch pair to constructing a dynamic landscape for two-step neural differentiation.The validity of Dawkins's selfish gene theory and the role of the unconscious in decision making.A Network Model to Describe the Terminal Differentiation of B CellsBistability, bifurcations, and Waddington's epigenetic landscape.Dynamical systems approach to endothelial heterogeneity.Dynamic Maternal Gradients Control Timing and Shift-Rates for Drosophila Gap Gene Expression.Gene regulatory network underlying the immortalization of epithelial cells.Critical Points in Tumorigenesis: A Carcinogen-Initiated Phase Transition Analyzed via Single-Cell Proteomics.Visualizing the appearance and disappearance of the attractor of differentiation using Raman spectral imaging.Cell population structure prior to bifurcation predicts efficiency of directed differentiation in human induced pluripotent cellsSuppression of endogenous lipogenesis induces reversion of the malignant phenotype and normalized differentiation in breast cancer.A dynamical-systems view of stem cell biology.When peers are not peers and don't know it: The Dunning-Kruger effect and self-fulfilling prophecy in peer-review.Genetic and non-genetic instability in tumor progression: link between the fitness landscape and the epigenetic landscape of cancer cells.The role of gene regulatory networks in promoting cancer progression and metastasis.Bioattractors: dynamical systems theory and the evolution of regulatory processes.Is epidemiology ready for epigenetics?Non-genetic cancer cell plasticity and therapy-induced stemness in tumour relapse: 'What does not kill me strengthens me'.Control of cancer formation by intrinsic genetic noise and microenvironmental cues.Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity.Envisioning metastasis as a transdifferentiation phenomenon clarifies discordant results on cancer.
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The molecular and mathematical basis of Waddington's epigenetic landscape: a framework for post-Darwinian biology?
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
The molecular and mathematical ...... rk for post-Darwinian biology?
@en
The molecular and mathematical ...... rk for post-Darwinian biology?
@nl
type
label
The molecular and mathematical ...... rk for post-Darwinian biology?
@en
The molecular and mathematical ...... rk for post-Darwinian biology?
@nl
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The molecular and mathematical ...... rk for post-Darwinian biology?
@en
The molecular and mathematical ...... rk for post-Darwinian biology?
@nl
P2860
P356
P1433
P1476
The molecular and mathematical ...... rk for post-Darwinian biology?
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P2093
P2860
P304
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10.1002/BIES.201100031
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P577
2011-11-18T00:00:00Z