about
The cysteine- and glycine-rich LIM domain protein CRP2 specifically interacts with a novel human protein (CRP2BP)LIM-domain protein cysteine- and glycine-rich protein 2 (CRP2) is a novel marker of hepatic stellate cells and binding partner of the protein inhibitor of activated STAT1Adenoviral expression of a transforming growth factor-beta1 antisense mRNA is effective in preventing liver fibrosis in bile-duct ligated ratsComparative evaluation of gene delivery devices in primary cultures of rat hepatic stellate cells and rat myofibroblastsAnalysis of polymorphic TGFB1 codons 10, 25, and 263 in a German patient group with non-syndromic cleft lip, alveolus, and palate compared with healthy adultsPharmacological Intervention in Hepatic Stellate Cell Activation and Hepatic FibrosisHepatoprotective and Anti-fibrotic Agents: It's Time to Take the Next StepPrimary cultures of glomerular parietal epithelial cells or podocytes with proven originMutational analysis and NMR spectroscopy of quail cysteine and glycine-rich protein CRP2 reveal an intrinsic segmental flexibility of LIM domainsSolution structure of the carboxyl-terminal LIM domain from quail cysteine-rich protein CRP2Structure and intramodular dynamics of the amino-terminal LIM domain from quail cysteine- and glycine-rich protein CRP2Lipocalin 2 (LCN2) Expression in Hepatic Malfunction and TherapyExercise-Induced Release of Pharmacologically Active Substances and Their Relevance for Therapy of Hepatic InjuryThe hop constituent xanthohumol exhibits hepatoprotective effects and inhibits the activation of hepatic stellate cells at different levelsCharacterization of Sno expression in malignant melanomaSuppression in transformed avian fibroblasts of a gene (crp) encoding a cysteine-rich protein containing LIM domainsIto cells are liver-resident antigen-presenting cells for activating T cell responsesThe cysteine-rich protein family of highly related LIM domain proteinsModern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targetsImmune surveillance of liver cancer in non-alcoholic fatty liver disease: excess lipids cause CD4 T-cells loss and promote hepatocellular carcinoma developmentVariable expression of cystatin C in cultured trans-differentiating rat hepatic stellate cellsExpression and functional analysis of endoglin in isolated liver cells and its involvement in fibrogenic Smad signallingAntisense strategy against PDGF B-chain proves effective in preventing experimental liver fibrogenesisPharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPARgamma and SMAD2/3-dependent pathwaysIdentification of endoglin in rat hepatic stellate cells: new insights into transforming growth factor beta receptor signalingEndoglin differentially modulates antagonistic transforming growth factor-beta1 and BMP-7 signalingPro-fibrogenic potential of PDGF-D in liver fibrosisFetuin-B, a liver-derived plasma protein is essential for fertilizationLIM-domain protein cysteine- and glycine-rich protein 2 (CRP2) is a novel marker of hepatic stellate cells and binding partner of the protein inhibitor of activated STAT1Proteomic profiling in Lipocalin 2 deficient mice under normal and inflammatory conditions.Changes of the hepatic proteome in murine models for toxically induced fibrogenesis and sclerosing cholangitis.Targeted disruption of the mouse Csrp2 gene encoding the cysteine- and glycine-rich LIM domain protein CRP2 result in subtle alteration of cardiac ultrastructureSerum proteomic profiling in patients with bladder cancer.The CSRP2BP histone acetyltransferase drives smooth muscle gene expressionFunctional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosisEndoglin in liver fibrogenesis: Bridging basic science and clinical practiceRecombinant expression, purification, and functional characterisation of connective tissue growth factor and nephroblastoma-overexpressed proteinFrom proteomic multimarker profiling to interesting proteins: thymosin-β(4) and kininogen-1 as new potential biomarkers for inflammatory hepatic lesions.Antifibrotic effects of CXCL9 and its receptor CXCR3 in livers of mice and humans.Proteomic tissue profiling for the improvement of grading of noninvasive papillary urothelial neoplasia.
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Ralf Weiskirchen
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Ralf Weiskirchen
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