N6-isopentenyladenosine improves nuclear shape in fibroblasts from humans with progeroid syndromes by inhibiting the farnesylation of prelamin A.
about
Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation.Gene-rich chromosomal regions are preferentially localized in the lamin B deficient nuclear blebs of atypical progeria cells.Sizing and shaping the nucleus: mechanisms and significance.Nuclear envelopathies: a complex LINC between nuclear envelope and pathology.Computational Exploration for Lead Compounds That Can Reverse the Nuclear Morphology in Progeria.Biomechanical Strain Exacerbates Inflammation on a Progeria-on-a-Chip Model.
P2860
N6-isopentenyladenosine improves nuclear shape in fibroblasts from humans with progeroid syndromes by inhibiting the farnesylation of prelamin A.
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N6-isopentenyladenosine improv ...... e farnesylation of prelamin A.
@en
N6-isopentenyladenosine improv ...... e farnesylation of prelamin A.
@nl
type
label
N6-isopentenyladenosine improv ...... e farnesylation of prelamin A.
@en
N6-isopentenyladenosine improv ...... e farnesylation of prelamin A.
@nl
prefLabel
N6-isopentenyladenosine improv ...... e farnesylation of prelamin A.
@en
N6-isopentenyladenosine improv ...... e farnesylation of prelamin A.
@nl
P2093
P2860
P50
P356
P1433
P1476
N6-isopentenyladenosine improv ...... he farnesylation of prelamin A
@en
P2093
Alba D'Alessandro
Chiara Laezza
Maria G Caruso
Maria Notarnicola
P2860
P304
P356
10.1111/FEBS.12544
P407
P577
2013-11-18T00:00:00Z