Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines.

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Appropriate Sequence for Afatinib and Cisplatin Combination Improves Anticancer Activity in Head and Neck Squamous Cell Carcinoma

P2860

Q57818008-23A9C2D3-0E46-42E2-8C9E-527D94A4123F

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Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines.

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http://www.wikidata.org/entity/Q52617485

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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name

Simultaneous targeting of EGFR ...... ous cell carcinoma cell lines.

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Simultaneous targeting of EGFR ...... ous cell carcinoma cell lines.

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type

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label

Simultaneous targeting of EGFR ...... ous cell carcinoma cell lines.

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Simultaneous targeting of EGFR ...... ous cell carcinoma cell lines.

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prefLabel

Simultaneous targeting of EGFR ...... ous cell carcinoma cell lines.

@en

Simultaneous targeting of EGFR ...... ous cell carcinoma cell lines.

@nl

P1476

Simultaneous targeting of EGFR ...... ous cell carcinoma cell lines.

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P2093

Erik Fransen

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Hasan Baysal

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Ines De Pauw

http://www.w3.org/2001/XMLSchema#string

Jan Baptist Vermorken

http://www.w3.org/2001/XMLSchema#string

Jolien Van den Bossche

http://www.w3.org/2001/XMLSchema#string

Patrick Pauwels

http://www.w3.org/2001/XMLSchema#string

Vanessa Deschoolmeester

http://www.w3.org/2001/XMLSchema#string

P2860

Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab

BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models

ErbB receptors: from oncogenes to targeted cancer therapies

Epidermal growth factor receptor inhibitors: coming of age

Target binding properties and cellular activity of afatinib (BIBW 2992), an irreversible ErbB family blocker

Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival.

Evaluation of EGFR gene copy number as a predictive biomarker for the efficacy of cetuximab in combination with chemotherapy in the first-line treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck: EXTREME study.

Predictive value of epidermal growth factor receptor expression for first-line chemotherapy plus cetuximab in patients with head and neck and colorectal cancer: analysis of data from the EXTREME and CRYSTAL studies.

Impact of human papilloma virus infection on the response of head and neck cancers to anti-epidermal growth factor receptor antibody therapy

Afatinib versus methotrexate as second-line treatment in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 1): an open-label, randomised phase 3 trial

P304

830-854

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scholarly article

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10.1002/1878-0261.12197

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An Wouters

Filip Lardon

Marc Peeters

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2018-05-01T00:00:00Z

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29603584

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cetuximab

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5983215

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Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines.

about

P2860

P2860

Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines.

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