The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition.

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Long noncoding RNA MLK7-AS1 promotes ovarian cancer cells progression by modulating miR-375/YAP1 axis

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The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition.

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The HER4-YAP1 axis promotes tr ...... al and mesenchymal transition.

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The HER4-YAP1 axis promotes tr ...... al and mesenchymal transition.

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The HER4-YAP1 axis promotes tr ...... al and mesenchymal transition.

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The HER4-YAP1 axis promotes tr ...... al and mesenchymal transition.

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The HER4-YAP1 axis promotes tr ...... al and mesenchymal transition.

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The HER4-YAP1 axis promotes tr ...... al and mesenchymal transition.

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The HER4-YAP1 axis promotes tr ...... ial and mesenchymal transition

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Fengping Li

http://www.w3.org/2001/XMLSchema#string

Guoxin Li

http://www.w3.org/2001/XMLSchema#string

Hao Liu

http://www.w3.org/2001/XMLSchema#string

Jiang Yu

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Jiaolong Shi

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Siyu Chen

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Tingyu Mou

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Wende Li

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Xingxing Yao

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Zheng Han

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A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor

PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.

Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial.

Nuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer.

Receptor tyrosine kinase ERBB4 mediates acquired resistance to ERBB2 inhibitors in breast cancer cells.

Global cancer statistics, 2012

Trastuzumab--mechanism of action and use in clinical practice

LIM and SH3 protein 1 induces TGFβ-mediated epithelial-mesenchymal transition in human colorectal cancer by regulating S100A4 expression.

The efficiency and safety of trastuzumab for advanced gastric and gastroesophageal cancer: a meta-analysis of five randomized controlled trials.

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s41388-018-0204-5

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3022-3038

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10.1038/S41388-018-0204-5

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English

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Xiaolong Qi

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2018-03-14T00:00:00Z

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29535422

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The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition.

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P2860

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The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition.

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