TET enzymes as oxygen-dependent tumor suppressors: exciting new avenues for cancer management.

about

Tet1 facilitates hypoxia tolerance by stabilizing the HIF-α proteins independent of its methylcytosine dioxygenase activity.DNA methylation/hydroxymethylation in melanoma.Modulating epigenetic memory through vitamins and TET: implications for regenerative medicine and cancer treatment.

P2860

Q46284307-73BB3142-C1C1-4D23-9611-DD54BF7B2FCA Q47119104-ED0BBA6A-876B-4623-AEAE-183713F65D22 Q50581791-1F63B04D-46F0-4F8B-AE87-A77EA06ED780

P2860

TET enzymes as oxygen-dependent tumor suppressors: exciting new avenues for cancer management.

Item

http://www.wikidata.org/entity/Q53762480

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年学术文章

@wuu

2016年学术文章

@zh-cn

2016年学术文章

@zh-hans

2016年学术文章

@zh-my

2016年学术文章

@zh-sg

2016年學術文章

@yue

2016年學術文章

@zh

2016年學術文章

@zh-hant

name

TET enzymes as oxygen-dependen ...... avenues for cancer management.

@en

TET enzymes as oxygen-dependen ...... avenues for cancer management.

@nl

type

Item

label

TET enzymes as oxygen-dependen ...... avenues for cancer management.

@en

TET enzymes as oxygen-dependen ...... avenues for cancer management.

@nl

prefLabel

TET enzymes as oxygen-dependen ...... avenues for cancer management.

@en

TET enzymes as oxygen-dependen ...... avenues for cancer management.

@nl

P1476

TET enzymes as oxygen-dependen ...... avenues for cancer management.

@en

P2093

Eva Galle

http://www.w3.org/2001/XMLSchema#string

P2860

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

Connections between TET proteins and aberrant DNA modification in cancer

Structural insight into substrate preference for TET-mediated oxidation

Mutational landscape and significance across 12 major cancer types

TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

Failure of high-dose vitamin C (ascorbic acid) therapy to benefit patients with advanced cancer. A controlled trial.

Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation.

Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors

P304

1445-1448

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

editorial

P356

10.2217/EPI-2016-0126

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Diether Lambrechts

Bernard Thienpont

P577

2016-10-13T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

27733058

http://www.w3.org/2001/XMLSchema#string

TET enzymes as oxygen-dependent tumor suppressors: exciting new avenues for cancer management.

about

P2860

P2860

TET enzymes as oxygen-dependent tumor suppressors: exciting new avenues for cancer management.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698