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Structural and Functional Analyses of a Conserved Hydrophobic Pocket of Flavivirus MethyltransferaseIdentification and Characterization of Novel Broad-Spectrum Inhibitors of the Flavivirus MethyltransferaseWest Nile Virus 5'-Cap Structure Is Formed by Sequential Guanine N-7 and Ribose 2'-O Methylations by Nonstructural Protein 5Structure and Function of Flavivirus NS5 MethyltransferaseDistinct RNA Elements Confer Specificity to Flavivirus RNA Cap Methylation EventsImmunoassay Targeting Nonstructural Protein 5 To Differentiate West Nile Virus Infection from Dengue and St. Louis Encephalitis Virus Infections and from Flavivirus VaccinationWest Nile Virus Methyltransferase Catalyzes Two Methylations of the Viral RNA Cap through a Substrate-Repositioning MechanismSeparate molecules of West Nile virus methyltransferase can independently catalyze the N7 and 2′-O methylations of viral RNA capCrystal structures of two alpha-like scorpion toxins: non-proline cis peptide bonds and implications for new binding site selectivity on the sodium channelThree-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,)Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteinsThree-dimensional structure of human gamma -glutamyl hydrolase. A class I glatamine amidotransferase adapted for a complex substateStructures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexesCrystal structure of pokeweed antiviral protein with well-defined sugars from seeds at 1.8A resolutionZinc Induces Dimerization of the Class II Major Histocompatibility Complex Molecule That Leads to Cooperative Binding to a SuperantigenCrystal structure of a complete ternary complex of TCR, superantigen and peptide-MHCX-ray snapshots of the maturation of an antibody response to a protein antigenNMR and X-ray analysis of structural additivity in metal binding site-swapped hybrids of rubredoxinCrystal Structure of the Mycoplasma arthritidis-Derived Mitogen in Apo Form Reveals a 3D Domain-Swapped DimerAnalysing the visible conformational substates of the FK506-binding protein FKBP12Pfit Is a Structurally Novel Crohn's Disease-Associated SuperantigenStructural basis of conformational transitions in the active site and 80′s loop in the FK506-binding protein FKBP12Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6Crystal structure of an acidic neurotoxin from scorpion Buthus martensii Karsch at 1.85 A resolutionCrystal structure of a T-cell receptor beta-chain complexed with a superantigenDual conformations of a T cell receptor V alpha homodimer: implications for variability in V alpha V beta domain associationStructure of the Vdelta domain of a human gammadelta T-cell antigen receptorA mutational analysis of binding interactions in an antigen-antibody protein-protein complexThree-dimensional structure of H-2Dd complexed with an immunodominant peptide from human immunodeficiency virus envelope glycoprotein 120Novel Broad Spectrum Inhibitors Targeting the Flavivirus MethyltransferaseA conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease.The structural basis of T cell activation by superantigens.Functional interaction of CD154 protein with α5β1 integrin is totally independent from its binding to αIIbβ3 integrin and CD40 moleculesThe flavivirus protease as a target for drug discovery.S-adenosyl-homocysteine is a weakly bound inhibitor for a flaviviral methyltransferaseFlavivirus RNA cap methyltransferase: structure, function, and inhibition.Zinc inhibits Hedgehog autoprocessing: linking zinc deficiency with Hedgehog activation5'-Silylated 3'-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue VirusCoupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor ProteinsInexpensive electronics and software for photon statistics and correlation spectroscopy
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P50
description
onderzoeker
@nl
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հետազոտող
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H. Li
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Hongmin Li
@de
Hongmin Li
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Hongmin Li
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Hongmin Li
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H Li
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H. Li
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Hongmin Li
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Hongmin Li
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Hongmin Li
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Hongmin Li
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P106
P108
P1153
36015611100
P2798
P31
P3835
hongmin-li4
P496
0000-0002-8684-5308