Chromomycin, mithramycin, and olivomycin binding sites on heterogeneous deoxyribonucleic acid. Footprinting with (methidiumpropyl-EDTA)iron(II).
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Mithramycin forms a stable dimeric complex by chelating with Fe(II): DNA-interacting characteristics, cellular permeation and cytotoxicityThe three-dimensional structure of the 4:1 mithramycin:d(ACCCGGGT)(2) complex: evidence for an interaction between the E saccharidesRegulatory mechanism of endothelin receptor B in the cerebral arteries after focal cerebral ischemiaSelf-catalyzed cyclization of the intervening sequence RNA of Tetrahymena: inhibition by methidiumpropyl.EDTA and localization of the major dye binding sitesDNA cleavage by hydroxy-salicylidene-ethylendiamine-iron complexes.Preferential, cooperative binding of DNA topoisomerase II to scaffold-associated regionsBacteriophage T4 DNA topoisomerase is the target of antitumor agent 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) in T4-infected Escherichia coliIn vivo topoisomerase II cleavage of the Drosophila histone and satellite III repeats: DNA sequence and structural characteristicsChemical footprinting of 5S RNA chromatin in embryos of Drosophila melanogasterPhosphorylation of the RNA-dependent protein kinase regulates its RNA-binding activity.A model for chromatin opening: stimulation of topoisomerase II and restriction enzyme cleavage of chromatin by distamycin.Mithramycin inhibits SP1 binding and selectively inhibits transcriptional activity of the dihydrofolate reductase gene in vitro and in vivo.Mithramycin blocks protein binding and function of the SV40 early promoter.Molecular recognition of B-DNA by Hoechst 33258.Transcription factor decoy (TFD) in breast cancer research and treatment.Methidiumpropyl-EDTA.Fe(II) and DNase I footprinting report different small molecule binding site sizes on DNAKetopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novPromoters of Human Cosmc and T-synthase Genes Are Similar in Structure, Yet Different in Epigenetic RegulationPCR-based development of DNA substrates containing modified bases: an efficient system for investigating the role of the exocyclic groups in chemical and structural recognition by minor groove binding drugs and proteins.Hepatitis C Virus Activates a Neuregulin-Driven Circuit to Modify Surface Expression of Growth Factor Receptors of the ErbB Family.Plant DNA flow cytometry and estimation of nuclear genome sizeInteraction of drugs with branched DNA structures.The conformation of the d(ACCCGGGT) duplex in aqueous solution.Some properties of new DNA-specific bisbenzimidazole fluorochromes without a piperazine ring.Organometallic Iridium(III) anticancer complexes with new mechanisms of action: NCI-60 screening, mitochondrial targeting, and apoptosis.Specific protein 1 depletion attenuates glucose uptake and proliferation of human glioma cells by regulating GLUT3 expression.Mithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegeneration.Differential effects of distamycin analogues on amplification of human gene sequences by polymerase-chain reaction.Structural basis of DNA recognition by anticancer antibiotics, chromomycin A(3), and mithramycin: roles of minor groove width and ligand flexibility.Differential interactions of antitumor antibiotics chromomycin A(3) and mithramycin with d(TATGCATA)(2) in presence of Mg(2+).Triple helix formation by purine-rich oligonucleotides targeted to the human dihydrofolate reductase promoter.NMR investigation of the interaction of mithramycin A with d(ACCCGGGT)2.Targeting of the HIV-1 long terminal repeat with chromomycin potentiates the inhibitory effects of a triplex-forming oligonucleotide on Sp1-DNA interactions and in vitro transcription.Modelling basic features of specificity in DNA-aureolic acid-derived antibiotic interactions.Theoretical analysis of the footprinting experiment.Binding of matrix attachment regions to lamin polymers involves single-stranded regions and the minor groove.Antitumour drug-DNA interactions: NMR studies of echinomycin and chromomycin complexes.A versatile in vivo footprinting technique using 1,10-phenanthroline-copper complex to study important cellular processes.Regulation of LRRK2 promoter activity and gene expression by Sp1.Elucidation of the DNA-interacting properties and anticancer activity of a Ni(II)-coordinated mithramycin dimer complex.
P2860
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P2860
Chromomycin, mithramycin, and olivomycin binding sites on heterogeneous deoxyribonucleic acid. Footprinting with (methidiumpropyl-EDTA)iron(II).
description
1983 nî lūn-bûn
@nan
1983年の論文
@ja
1983年学术文章
@wuu
1983年学术文章
@zh-cn
1983年学术文章
@zh-hans
1983年学术文章
@zh-my
1983年学术文章
@zh-sg
1983年學術文章
@yue
1983年學術文章
@zh
1983年學術文章
@zh-hant
name
Chromomycin, mithramycin, and ...... methidiumpropyl-EDTA)iron(II).
@en
Chromomycin, mithramycin, and ...... methidiumpropyl-EDTA)iron(II).
@nl
type
label
Chromomycin, mithramycin, and ...... methidiumpropyl-EDTA)iron(II).
@en
Chromomycin, mithramycin, and ...... methidiumpropyl-EDTA)iron(II).
@nl
prefLabel
Chromomycin, mithramycin, and ...... methidiumpropyl-EDTA)iron(II).
@en
Chromomycin, mithramycin, and ...... methidiumpropyl-EDTA)iron(II).
@nl
P356
P1433
P1476
Chromomycin, mithramycin, and ...... methidiumpropyl-EDTA)iron(II).
@en
P2093
Van Dyke MW
P304
P356
10.1021/BI00279A011
P407
P577
1983-05-01T00:00:00Z