about
The endosomal-lysosomal system: from acidification and cargo sorting to neurodegenerationProteomics of protein post-translational modifications implicated in neurodegenerationIdentification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexesPseudomonas aeruginosa EftM Is a Thermoregulated MethyltransferaseThe cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis.U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21.Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease.A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activationAggregates of small nuclear ribonucleic acids (snRNAs) in Alzheimer's disease.Proteomic analysis of hippocampal dentate granule cells in frontotemporal lobar degeneration: application of laser capture technology.Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitinationConsequences of impaired purine recycling on the proteome in a cellular model of Lesch-Nyhan disease.Quantitative phosphoproteomics of Alzheimer's disease reveals cross-talk between kinases and small heat shock proteins.Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease.Tissue-type plasminogen activator regulates the neuronal uptake of glucose in the ischemic brain.Transcriptional regulation of adrenocortical steroidogenic gene expression.Expression, purification and proteomic analysis of recombinant histone H4 acetylated at lysine 16.U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.Phosphorylation of CtBP1 by cAMP-dependent protein kinase modulates induction of CYP17 by stimulating partnering of CtBP1 and 2.Multiple Signaling Pathways Coordinate CYP17 Gene Expression in the Human Adrenal CortexBiochemical isolation of myonuclei employed to define changes to the myonuclear proteome that occur with aging.Integrating Next-Generation Genomic Sequencing and Mass Spectrometry To Estimate Allele-Specific Protein Abundance in Human Brain.Protein profiling of active cysteine cathepsins in living cells using an activity-based probe containing a cell-penetrating peptide.Osteopontin Is a Blood Biomarker for Microglial Activation and Brain Injury in Experimental Hypoxic-Ischemic Encephalopathy.Resveratrol stimulates cortisol biosynthesis by activating SIRT-dependent deacetylation of P450sccNeuron enriched nuclear proteome isolated from human brain.Quantitative proteomics reveals significant changes in cell shape and an energy shift after IPTG induction via an optimized SILAC approach for Escherichia coli.Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway.A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain.Characterization of Detergent Insoluble Proteome in Chronic Traumatic Encephalopathy.Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases.Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.Novel mouse models of oculopharyngeal muscular dystrophy (OPMD) reveal early onset mitochondrial defects and suggest loss of PABPN1 may contribute to pathology.Differential Phagocytic Properties of CD45low Microglia and CD45high Brain Mononuclear Phagocytes-Activation and Age-Related Effects.Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease.Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins.Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with diseaseThe Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's diseaseEffects of Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's DiseaseLarge-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age
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researcher
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wetenschapper
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հետազոտող
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Eric B Dammer
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Eric B Dammer
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Eric B Dammer
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Eric B Dammer
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Eric B Dammer
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Eric B Dammer
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Eric B Dammer
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Eric B Dammer
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Eric B Dammer
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Eric B Dammer
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Eric Dammer
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Eric B Dammer
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Eric B Dammer
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Eric B Dammer
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Eric B Dammer
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Eric B Dammer
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P106
P108
P2798
P31
P496
0000-0003-2947-7606