about
A transposon-based genetic screen in mice identifies genes altered in colorectal cancerThe stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesisMicroRNA-26b represses colon cancer cell proliferation by inhibiting lymphoid enhancer factor 1 expression.Somatic mutagenesis with a Sleeping Beauty transposon system leads to solid tumor formation in zebrafish.Conditional deletion of Sox17 reveals complex effects on uterine adenogenesis and functionNucleotide bias observed with a short SELEX RNA aptamer libraryNovel molecular and computational methods improve the accuracy of insertion site analysis in Sleeping Beauty-induced tumors.Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse modelMammalian germ-line transgenesis by transposition.Gene transfer into genomes of human cells by the sleeping beauty transposon system.Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesisA Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesisSequencing methods and datasets to improve functional interpretation of sleeping beauty mutagenesis screens.Cell-internalization SELEX: method for identifying cell-internalizing RNA aptamers for delivering siRNAs to target cellsCell of origin strongly influences genetic selection in a mouse model of T-ALLClonal selection drives genetic divergence of metastatic medulloblastoma.Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinomaRNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screensSex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR.Sleeping beauty: a novel cancer gene discovery tool.Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma.Characterization of transgenic mice expressing cancer-associated variants of human NOTCH1A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice.Divergent clonal selection dominates medulloblastoma at recurrenceA conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.A Hybrid Adenoviral Vector System Achieves Efficient Long-Term Gene Expression in the Liver via piggyBac Transposition.A Trp53fl/flPtenfl/fl mouse model of undifferentiated pleomorphic sarcoma mediated by adeno-Cre injection and in vivo bioluminescence imaging.A Transposon-based Analysis Reveals RASA1 Is Involved in Triple-Negative Breast Cancer.A transposon-based analysis of gene mutations related to skin cancer development.Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal.The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity.Transposon mutagenesis identifies candidate genes that cooperate with loss of transforming growth factor-beta signaling in mouse intestinal neoplasms.Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors.Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma in mice.Transposon mutagenesis identifies chromatin modifiers cooperating with Ras in thyroid tumorigenesis and detects ATXN7 as a cancer gene.A simplified transposon mutagenesis method to perform phenotypic forward genetic screens in cultured cells
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description
researcher
@en
ricercatore
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հետազոտող
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name
Adam J. Dupuy
@ast
Adam J. Dupuy
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Adam J. Dupuy
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Adam J. Dupuy
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Adam J. Dupuy
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type
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Adam J. Dupuy
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Adam J. Dupuy
@en
Adam J. Dupuy
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Adam J. Dupuy
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Adam J. Dupuy
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Adam J. Dupuy
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Adam J. Dupuy
@en
Adam J. Dupuy
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Adam J. Dupuy
@nl
Adam J. Dupuy
@sl
P214
P106
P1153
7005361324
P21
P214
P31
P496
0000-0002-8561-4911
P734
P735
P7859
lccn-n2011181941