about
SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activitiesTargeting epigenetic pathways in acute myeloid leukemia and myelodysplastic syndrome: a systematic review of hypomethylating agents trialsSlow progressive conduction and contraction defects in loss of Nkx2-5 mice after cardiomyocyte terminal differentiationModulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variantsDNA methylation and human diseaseSpecific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD).Roles of cell division and gene transcription in the methylation of CpG islands.Comparative epigenomics of human and mouse mammary tumors.DNA methylation: superior or subordinate in the epigenetic hierarchy?Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells.Epigenetic silencing of the tumor suppressor cystatin M occurs during breast cancer progression.The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas.Epigenetic signatures of alcohol abuse and hepatitis infection during human hepatocarcinogenesis.DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (CPS1) in human hepatocellular carcinoma.DNA methylation and chromatin - unraveling the tangled web.Epigenetic mechanisms and genome stability.Small molecule inhibitor YM155-mediated activation of death receptor 5 is crucial for chemotherapy-induced apoptosis in pancreatic carcinoma.Targeted bisulfite sequencing by solution hybrid selection and massively parallel sequencing.Stealth technology: how Epstein-Barr virus utilizes DNA methylation to cloak itself from immune detection.iTagPlot: an accurate computation and interactive drawing tool for tag density plot.High fat diet and exercise lead to a disrupted and pathogenic DNA methylome in mouse liver.CAME: identification of chromatin accessibility from nucleosome occupancy and methylome sequencing.Transcriptional activation of the Epstein-Barr virus latency C promoter after 5-azacytidine treatment: evidence that demethylation at a single CpG site is crucial.Histone deacetylase inhibitors for cancer therapy.Nucleosome positioning changes during human embryonic stem cell differentiation.DNA methylation in development and human diseaseDNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions.DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer.A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding.DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function.Focal adhesion kinase inhibitor PF573228 and death receptor 5 agonist lexatumumab synergistically induce apoptosis in pancreatic carcinoma.Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma.Acute depletion redefines the division of labor among DNA methyltransferases in methylating the human genome.Impact of human MLL/COMPASS and polycomb complexes on the DNA methylome.Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells.Initiation of aberrant DNA methylation patterns and heterogeneity in precancerous lesions of human hepatocellular cancer.DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.A Novel Vaccine Targeting Glypican-3 as a Treatment for Hepatocellular Carcinoma.An EBF3-mediated transcriptional program that induces cell cycle arrest and apoptosis.Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma.
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description
researcher
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wetenschapper
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հետազոտող
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name
Keith D. Robertson
@ast
Keith D. Robertson
@en
Keith D. Robertson
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Keith D. Robertson
@nl
Keith D. Robertson
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type
label
Keith D. Robertson
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Keith D. Robertson
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Keith D. Robertson
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Keith D. Robertson
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Keith D. Robertson
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prefLabel
Keith D. Robertson
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Keith D. Robertson
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Keith D. Robertson
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Keith D. Robertson
@nl
Keith D. Robertson
@sl
P106
P108
P1153
35994002600
P31
P496
0000-0002-7508-3328