Characterization of Covalent-Reversible EGFR Inhibitors.

about

Characterization of Covalent-Reversible EGFR Inhibitors.

Item

http://www.wikidata.org/entity/Q55317607

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年学术文章

@wuu

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh

2017年學術文章

@zh-hant

name

Characterization of Covalent-Reversible EGFR Inhibitors.

@en

Characterization of Covalent-Reversible EGFR Inhibitors.

@nl

type

Item

label

Characterization of Covalent-Reversible EGFR Inhibitors.

@en

Characterization of Covalent-Reversible EGFR Inhibitors.

@nl

prefLabel

Characterization of Covalent-Reversible EGFR Inhibitors.

@en

Characterization of Covalent-Reversible EGFR Inhibitors.

@nl

P1476

Characterization of Covalent-Reversible EGFR Inhibitors

@en

P2093

Daniel Rauh

http://www.w3.org/2001/XMLSchema#string

Debjit Basu

http://www.w3.org/2001/XMLSchema#string

Julian Engel

http://www.w3.org/2001/XMLSchema#string

Marina Keul

http://www.w3.org/2001/XMLSchema#string

Simone Eppmann

http://www.w3.org/2001/XMLSchema#string

Steven Smith

http://www.w3.org/2001/XMLSchema#string

P2860

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models

Ten things you should know about protein kinases: IUPHAR Review 14

Targeting cancer with kinase inhibitors

Electrophilic Fragment-Based Design of Reversible Covalent Kinase Inhibitors

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

Identification of potent and selective cathepsin S inhibitors containing different central cyclic scaffolds

Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach

Insight into the Inhibition of Drug-Resistant Mutants of the Receptor Tyrosine Kinase EGFR

P304

1563-1575

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1021/ACSOMEGA.7B00157

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2017-04-20T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

29963651

http://www.w3.org/2001/XMLSchema#string

P932

6018958

http://www.w3.org/2001/XMLSchema#string