about
Physiological level production of antigen-specific human immunoglobulin in cloned transchromosomic cattleProduction of Potent Fully Human Polyclonal Antibodies against Ebola Zaire Virus in Transchromosomal CattlePrecision genetics for complex objectives in animal agriculture.Artificial chromosome vectors and expression of complex proteins in transgenic animals.Triple immunoglobulin gene knockout transchromosomic cattle: bovine lambda cluster deletion and its effect on fully human polyclonal antibody production.Species-Specific Chromosome Engineering Greatly Improves Fully Human Polyclonal Antibody Production Profile in Cattle.Human Polyclonal Antibodies Produced through DNA Vaccination of Transchromosomal Cattle Provide Mice with Post-Exposure Protection against Lethal Zaire and Sudan Ebolaviruses.Commercialising genetically engineered animal biomedical products.Human polyclonal antibodies produced in transchromosomal cattle prevent lethal Zika virus infection and testicular atrophy in mice.Clostridium difficile chimeric toxin receptor binding domain vaccine induced protection against different strains in active and passive challenge models.Antibody Preparations from Human Transchromosomic Cows Exhibit Prophylactic and Therapeutic Efficacy against Venezuelan Equine Encephalitis Virus.Bovine viral diarrhea virus (BVDV) in cell lines used for somatic cell cloning.Cloned calves from chromatin remodeled in vitro.Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo.DNA vaccine-derived human IgG produced in transchromosomal bovines protect in lethal models of hantavirus pulmonary syndrome.Histone H1 kinase activity in bovine oocytes following calcium stimulation.Sequential targeting of the genes encoding immunoglobulin-mu and prion protein in cattle.Safety and tolerability of a novel, polyclonal human anti-MERS coronavirus antibody produced from transchromosomic cattle: a phase 1 randomised, double-blind, single-dose-escalation study.Deployment of Transchromosomal Bovine for Personalized Antimicrobial Therapy.Reducing the amount of cytoplasm available for early embryonic development decreases the quality but not quantity of embryos produced by in vitro fertilization and nuclear transplantation.Cloned transchromosomic calves producing human immunoglobulinHuman Polyclonal Antibodies Produced from Transchromosomal Bovine Provides Prophylactic and Therapeutic Protections Against Zika Virus Infection in KO Syrian HamstersGeneration of H7N9-specific human polyclonal antibodies from a transchromosomic goat (caprine) systemOral delivery of Hyperimmune bovine serum antibodies against CS6-expressing enterotoxigenic Escherichia coli as a prophylactic against diarrheaLipid Nanoparticle Formulation Increases Efficiency of DNA-Vectored Vaccines/Immunoprophylaxis in Animals Including Transchromosomic Bovines
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description
onderzoeker
@nl
researcher
@en
հետազոտող
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name
Eddie J. Sullivan
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Eddie J. Sullivan
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Eddie J. Sullivan
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Eddie J. Sullivan
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Eddie J. Sullivan
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Eddie J. Sullivan
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Eddie J. Sullivan
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Eddie J. Sullivan
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Eddie J. Sullivan
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Eddie J. Sullivan
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Eddie J. Sullivan
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Eddie J. Sullivan
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Eddie J. Sullivan
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Eddie J. Sullivan
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Eddie J. Sullivan
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P106
P1153
7201723211
P21
P31
P496
0000-0001-7468-2006