Gain-of-Function (GOF) Mutant p53 as Actionable Therapeutic Target.

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Gain-of-Function (GOF) Mutant p53 as Actionable Therapeutic Target.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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Gain-of-Function (GOF) Mutant p53 as Actionable Therapeutic Target.

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Gain-of-Function

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type

Item

label

Gain-of-Function (GOF) Mutant p53 as Actionable Therapeutic Target.

@en

Gain-of-Function

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Gain-of-Function (GOF) Mutant p53 as Actionable Therapeutic Target.

@en

Gain-of-Function

@nl

P1476

Gain-of-Function (GOF) Mutant p53 as Actionable Therapeutic Target.

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P2093

Ramona Schulz-Heddergott

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Ute M Moll

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P2860

Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway

Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function

Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis

Mutant p53: One, No One, and One Hundred Thousand

Reactivating mutant p53 using small molecules as zinc metallochaperones: awakening a sleeping giant in cancer

Small Molecule Inhibitors to Disrupt Protein-protein Interactions of Heat Shock Protein 90 Chaperone Machinery

Targeted rescue of a destabilized mutant of p53 by an in silico screened drug

Small molecule induced reactivation of mutant p53 in cancer cells

Inhibition of MDM2 by hsp90 contributes to mutant p53 stabilization

Targeting the dynamic HSP90 complex in cancer

P31

scholarly article

P356

10.3390/CANCERS10060188

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P433

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P478

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P577

2018-06-07T00:00:00Z

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P698

29875343

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P932

6025530

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