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Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Leads to Hypogonadism and Infertility.Homeodomain Proteins SIX3 and SIX6 Regulate Gonadotrope-specific Genes During Pituitary Development.Heterozygous deletion of ventral anterior homeobox (vax1) causes subfertility in miceKisspeptin regulates gonadotropin genes via immediate early gene induction in pituitary gonadotropesLong-lasting impairment of mGluR5-activated intracellular pathways in the striatum after withdrawal of cocaine self-administrationInteractions between intracellular domains as key determinants of the quaternary structure and function of receptor heteromers.Dopamine D1-histamine H3 receptor heteromers provide a selective link to MAPK signaling in GABAergic neurons of the direct striatal pathway.Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: σ1-D1-H3 receptor complexes as key targets for reducing cocaine's effects.Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines.Transcriptional interaction between cFOS and the homeodomain-binding transcription factor VAX1 on the GnRH promoter controls Gnrh1 expression levels in a GnRH neuron maturation specific manner.Haploinsufficiency of SIX3 Abolishes Male Reproductive Behavior Through Disrupted Olfactory Development, and Impairs Female Fertility Through Disrupted GnRH Neuron Migration.Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and RatsEditorial: Hormone release patterns in mammalsCircadian rhythms in the mouse reproductive axis during the estrous cycle and pregnancyThe Homeodomain Transcription Factors Vax1 and Six6 Are Required for SCN Development and FunctionRole of core circadian clock genes in hormone release and target tissue sensitivity in the reproductive axisDifferential CRE Expression in Lhrh-cre and GnRH-cre Alleles and the Impact on Fertility in Otx2-Flox MiceDeletion of the Homeodomain Protein Six6 From GnRH Neurons Decreases GnRH Gene Expression, Resulting in InfertilityA small population of hypothalamic neurons govern fertility: the critical role of VAX1 in GnRH neuron development and fertility maintenance
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Hanne M Hoffmann
@ast
Hanne M Hoffmann
@en
Hanne M Hoffmann
@es
Hanne M Hoffmann
@nl
Hanne M Hoffmann
@sl
type
label
Hanne M Hoffmann
@ast
Hanne M Hoffmann
@en
Hanne M Hoffmann
@es
Hanne M Hoffmann
@nl
Hanne M Hoffmann
@sl
prefLabel
Hanne M Hoffmann
@ast
Hanne M Hoffmann
@en
Hanne M Hoffmann
@es
Hanne M Hoffmann
@nl
Hanne M Hoffmann
@sl
P106
P31
P496
0000-0003-1555-1369