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Cyclohexenyl nucleic acids: conformationally flexible oligonucleotidesStructure Determination of the Top-Loop of the Conserved 3′-Terminal Secondary Structure in the Genome of FlavivirusesSolution structure of a HNA-RNA hybridStructure of the pyrimidine-rich internal loop in the poliovirus 3'-UTR: the importance of maintaining pseudo-2-fold symmetry in RNA helices containing two adjacent non-canonical base-pairsCleavage of DNA without loss of genetic information by incorporation of a disaccharide nucleosideDesign of Bioactive Peptides from Naturally Occurring -Conotoxin StructuresPc16a, the first characterized peptide from Conus pictus venom, shows a novel disulfide connectivityStructure-Function Elucidation of a New -Conotoxin, Lo1a, from Conus longurionisThe biolabile 2'-O-pivaloyloxymethyl modification in an RNA helix: an NMR solution structureContribution of dihydrouridine in folding of the D-arm in tRNAStructural and Functional Elucidation of Peptide Ts11 Shows Evidence of a Novel Subfamily of Scorpion Venom ToxinsThe protein phosphatase 2A phosphatase activator is a novel peptidyl-prolyl cis/trans-isomerase.Discovery of an acyclic nucleoside phosphonate that inhibits Mycobacterium tuberculosis ThyX based on the binding mode of a 5-alkynyl substrate analogue.A synthetic substrate of DNA polymerase deviating from the bases, sugar, and leaving group of canonical deoxynucleoside triphosphates.Phage display-directed discovery of LEDGF/p75 binding cyclic peptide inhibitors of HIV replication.A PKS/NRPS/FAS hybrid gene cluster from Serratia plymuthica RVH1 encoding the biosynthesis of three broad spectrum, zeamine-related antibiotics.Synthesis and structure-activity relationship studies of 2-(1,3,4-oxadiazole-2(3H)-thione)-3-amino-5-arylthieno[2,3-b]pyridines as inhibitors of DRAK2.Structural basis for the high Ca2+ affinity of the ubiquitous SERCA2b Ca2+ pump.Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish.Synthesis and in vitro enzymatic and antiviral evaluation of phosphoramidate d4T derivatives as chain terminators.RNase H mediated cleavage of RNA by cyclohexene nucleic acid (CeNA).Difference in conformational diversity between nucleic acids with a six-membered 'sugar' unit and natural 'furanose' nucleic acids.Discovery of a new Mycobacterium tuberculosis thymidylate synthase X inhibitor with a unique inhibition profile.NMR study on the interaction of the conserved CREX 'stem-loop' in the Hepatitis E virus genome with a naphthyridine-based ligand.NMR-based conformational analysis of 2',6-disubstituted uridines and antiviral evaluation of new phosphoramidate prodrugs.Isoguanine and 5-methyl-isocytosine bases, in vitro and in vivo.Hydroxy fatty acids for the delivery of dideoxynucleosides as anti-HIV agents.Identification of small peptides inhibiting the integrase-LEDGF/p75 interaction through targeting the cellular co-factor.The naturally occurring N6-threonyl adenine in anticodon loop of Schizosaccharomyces pombe tRNAi causes formation of a unique U-turn motif.Xylonucleic acid: synthesis, structure, and orthogonal pairing properties.Synthesis and evaluation of 5-substituted 2'-deoxyuridine monophosphate analogues as inhibitors of flavin-dependent thymidylate synthase in Mycobacterium tuberculosis.Design and synthesis of nucleolipids as possible activated precursors for oligomer formation via intramolecular catalysis: stability study and supramolecular organization.Synthesis and biological evaluation of 68Ga-bis-DOTA-PA as a potential agent for positron emission tomography imaging of necrosis.(D)- and (L)-cyclohexenyl-G, a new class of antiviral agents: synthesis, conformational analysis, molecular modeling, and biological activity.Alpha-homo-DNA and RNA form a parallel oriented non-A, non-B-type double helical structure.Structure of the alpha-homo-DNA:RNA duplex and the function of twist and slide to catalogue nucleic acid duplexes.A short path synthesis of [13C/15N] multilabeled pyrimidine nucleosides starting from glucopyranose nucleosides.Synthesis and properties of phosphorylated 3'-O-beta-D-ribofuranosyl-2'-deoxythymidine.Synthesis and conformational properties of O-beta-D-ribofuranosyl-(1''-2')-guanosine and (adenosine)-5''-phosphate.Dipeptides as leaving group in the enzyme-catalyzed DNA synthesis.
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Eveline Lescrinier
@ast
Eveline Lescrinier
@en
Eveline Lescrinier
@es
Eveline Lescrinier
@nl
Eveline Lescrinier
@sl
type
label
Eveline Lescrinier
@ast
Eveline Lescrinier
@en
Eveline Lescrinier
@es
Eveline Lescrinier
@nl
Eveline Lescrinier
@sl
prefLabel
Eveline Lescrinier
@ast
Eveline Lescrinier
@en
Eveline Lescrinier
@es
Eveline Lescrinier
@nl
Eveline Lescrinier
@sl
P106
P21
P31
P496
0000-0001-7066-4329