about
Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's diseaseGWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci.The PSEN1, p.E318G variant increases the risk of Alzheimer's disease in APOE-ε4 carriersNeurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanismsReceptor-associated protein (RAP) plays a central role in modulating Abeta deposition in APP/PS1 transgenic mice.Immature copper-zinc superoxide dismutase and familial amyotrophic lateral sclerosis.Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's diseaseCoding variants in TREM2 increase risk for Alzheimer's diseaseAggregation modulating elements in mutant human superoxide dismutase 1.Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammationAlzheimer's disease risk genes and mechanisms of disease pathogenesisExpression of novel Alzheimer's disease risk genes in control and Alzheimer's disease brains.Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseasesGenetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies.Missense mutations in progranulin gene associated with frontotemporal lobar degeneration: study of pathogenetic featuresBKCa channel regulates calcium oscillations induced by alpha-2-macroglobulin in human myometrial smooth muscle cells.Role of mutant SOD1 disulfide oxidation and aggregation in the pathogenesis of familial ALSCalcium phosphatase calcineurin influences tau metabolism.An examination of alpha B-crystallin as a modifier of SOD1 aggregate pathology and toxicity in models of familial amyotrophic lateral sclerosis.Alzheimer's disease genetics: from the bench to the clinic.A limited role for disulfide cross-linking in the aggregation of mutant SOD1 linked to familial amyotrophic lateral sclerosis.Novel progranulin variants do not disrupt progranulin secretion and cleavage.An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem CellsScalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening.Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition.Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience.Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.Correction to: Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience.Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.CXCR4 involvement in neurodegenerative diseases.Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum.Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure.Tau Kinetics in Neurons and the Human Central Nervous SystemDissecting the genetic relationship between cardiovascular risk factors and Alzheimer's diseaseWhite matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's diseaseRegionally specific TSC1 and TSC2 gene expression in tuberous sclerosis complexUtility of perfusion PET measures to assess neuronal injury in Alzheimer's diseaseCSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline
P50
Q24312938-6E599F65-9325-407F-982A-EF721F1C03E7Q29417137-949E553F-71BB-4086-9659-A00DE4ED7B56Q30360286-2DCD1CD2-1E51-4F90-9A08-8FB3E9C581E1Q31129910-AFEC3F7A-FD93-4C26-9C29-D210106FB2B8Q31814881-FA471FB4-5AF7-4858-A7DB-776C555B98EBQ33367579-2358889A-279C-41E6-A82C-F0F8F081E0D1Q33772493-0D6E8194-65A9-49F0-9E23-00EB83985F2DQ33828778-9AE0D0E6-6CA7-4529-87AA-51434C5EA099Q34307280-71B25628-D69C-428D-836C-3F923E517229Q34383094-27FE8FFE-4797-48EE-A2FB-07E39734FF73Q34394932-8606BCE6-B26E-407C-88DC-22F9A2433D11Q34425904-0AEEE05A-2AF0-400E-98DB-C36FD15CD408Q34506196-1B3E4F3C-287D-4950-990E-07DD3F125F37Q34546133-55D9EA17-F4B5-4C32-A9A8-E5C146BF7C19Q36316307-DAE4A7E2-DF8D-4D6A-87A2-32AD1A1C361BQ36466732-D3D0A0B4-AFCB-44C8-BC12-B72CDC4661B7Q36535668-EB62950A-9D83-467C-9A5D-C1149ECE680DQ36831594-748F20C1-B9F1-4C32-BD26-BD23FD6AA3F1Q37175256-6D06FA54-4551-4F0B-B3E4-722822DA7020Q37427768-0A3BC1E3-6BEF-4A33-B48E-0462A1D3A535Q37677565-00285702-1B5D-4A5A-996C-FAB7CFC48A68Q38225911-87519626-990E-47CB-9B14-1C66F1B4CFF6Q38291545-680BCFA2-33BC-4EB8-B398-14B20E69DD39Q39140598-C20298C8-A3F9-4ABB-AB9C-2541A803F3CDQ41327539-F712B3C2-61DD-46C6-B8D6-E59D82DD9DF8Q42376445-533ABDFB-91F4-4E07-8DDE-24AFD8551306Q46585136-26B47D87-B8FD-41F7-BCB9-B5ACA42BF5A9Q47139003-BEB4FEA8-59F0-453B-BF94-978ACA847952Q47218394-EC6975E7-306A-4703-B83F-250F5A3B584BQ47564143-64BE6306-C43E-4406-82EC-1C71BF33D40BQ48509982-6949AFF6-FE9C-43A7-ACA2-F1C9FD7E1549Q52317581-2EF07361-FF4D-4EF5-B682-BE0621F77DAAQ53513139-1C3C2DC7-C702-48BE-8324-19E4149D6BD6Q55479814-098C04AB-5815-4613-BE32-EBC0D03EB3BFQ57215461-3677F84F-40B7-4611-A883-411F7EC029EFQ58558715-9D460F17-F304-425B-939C-D12A2AD4AD3BQ58698141-0EC30C91-A0CC-4507-83F4-005F3D9A98BEQ58762014-92B27896-D90E-46B2-A1D0-7BA43D71C8BBQ59126759-4B0A7652-4FF3-4E8C-803E-1CA7D39AE242Q59806735-6A8E3507-671E-41AB-BDC2-14534A7D44CC
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Celeste M Karch
@ast
Celeste M Karch
@en
Celeste M Karch
@es
Celeste M Karch
@nl
type
label
Celeste M Karch
@ast
Celeste M Karch
@en
Celeste M Karch
@es
Celeste M Karch
@nl
altLabel
Celeste Karch
@en
prefLabel
Celeste M Karch
@ast
Celeste M Karch
@en
Celeste M Karch
@es
Celeste M Karch
@nl
P106
P1153
24460265800
P31
P496
0000-0002-6854-5547