about
Structural studies of Ets-1/Pax5 complex formation on DNAOpposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactylyAn inhibitory carboxyl-terminal domain in Ets-1 and Ets-2 mediates differential binding of ETS family factors to promoter sequences of the mb-1 geneDe Novo Mutations in EBF3 Cause a Neurodevelopmental SyndromeIdentification of an Sp factor-dependent promoter in GCET, a gene expressed at high levels in germinal center B cells.Compound haploinsufficiencies of Ebf1 and Runx1 genes impede B cell lineage progressionA global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate.Structural insights into histone demethylation by JMJD2 family members.The Mi-2/NuRD complex: a critical epigenetic regulator of hematopoietic development, differentiation and cancer.Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site.Roles of EBF and Pax-5 in B lineage commitment and development.A dose-dependent role for EBF1 in repressing non-B-cell-specific genes.Mi-2/NuRD chromatin remodeling complexes regulate B and T-lymphocyte development and function.Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiencyInflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor.Requirements for selective recruitment of Ets proteins and activation of mb-1/Ig-alpha gene transcription by Pax-5 (BSAP).Beryllium-induced TNF-alpha production is transcription-dependent in chronic beryllium disease.MBD2 and multiple domains of CHD4 are required for transcriptional repression by Mi-2/NuRD complexesAutoimmune vitiligo is associated with gain-of-function by a transcriptional regulator that elevates expression of HLA-A*02:01 in vivo."Hands-on" regulation of B cell development by the transcription factor Pax5.The 'zinc knuckle' motif of Early B cell Factor is required for transcriptional activation of B cell-specific genes.Opposing effects of SWI/SNF and Mi-2/NuRD chromatin remodeling complexes on epigenetic reprogramming by EBF and Pax5.Highly cooperative recruitment of Ets-1 and release of autoinhibition by Pax5.The steroidogenic enzyme Cyp11a1 is essential for development of peanut-induced intestinal anaphylaxis.Ikaros promotes rearrangement of TCR α genes in an Ikaros null thymoma cell line.Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription.Regulation of gene expression at early stages of B-cell differentiation.Spontaneous loss of B lineage transcription factors leads to pre-B leukemia in Ebf1+/-Bcl-xLTg miceCharacterization of adrenocorticotropin receptors that appear when 3T3-L1 cells differentiate into adipocytes.Deregulation of kinase signaling and lymphoid development in EBF1-PDGFRB ALL leukemogenesis.The transcription factors GATA2 and microphthalmia-associated transcription factor regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis.Clipping of arginine-methylated histone tails by JMJD5 and JMJD7.Human leukocyte interferon has no structural or biological relationship to corticotropinA sensitive radioimmunoassay for corticotropin using a fully biologically active 125I-labeled ligandSynthesis of human corticotropinyl-thiolglycine and its specific conjugation to bovine serum albuminExpression of a non-DNA-binding Ikaros isoform exclusively in B cells leads to autoimmunity but not leukemogenesisTranscription factor Pax5 (BSAP) transactivates the RAG-mediated V(H)-to-DJ(H) rearrangement of immunoglobulin genesConveying the message: identification of Ig-alpha and Ig-beta as components of the B cell receptor complexEditorial overview: Lymphocyte development and activation: Lymphoid cell differentiation: choosing paths to traverse the immune landscapeZinc Finger Protein 521 Regulates Early Hematopoiesis through Cell-Extrinsic Mechanisms in the Bone Marrow Microenvironment
P50
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P50
description
researcher
@en
wetenschapper
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հետազոտող
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name
James R Hagman
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James R Hagman
@en
James R Hagman
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James R Hagman
@nl
type
label
James R Hagman
@ast
James R Hagman
@en
James R Hagman
@es
James R Hagman
@nl
prefLabel
James R Hagman
@ast
James R Hagman
@en
James R Hagman
@es
James R Hagman
@nl
P106
P1153
7004576547
P21
P31
P496
0000-0002-5436-8455