about
Comparative analysis of translation efficiencies of hepatitis C virus 5' untranslated regions among intraindividual quasispecies present in chronic infection: opposite behaviors depending on cell typeAntisense oligonucleotides targeted to the domain IIId of the hepatitis C virus IRES compete with 40S ribosomal subunit binding and prevent in vitro translationA functional selection of viral genetic elements in cultured cells to identify hepatitis C virus RNA translation inhibitorsNMR structure of a kissing complex formed between the TAR RNA element of HIV-1 and a LNA-modified aptamerLiquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complexInhibition of pre-mRNA splicing by a synthetic Blom7α-interacting small RNAEx Vivo and In Vivo Imaging and Biodistribution of Aptamers Targeting the Human Matrix MetalloProtease-9 in MelanomasTowards the selection of phosphorothioate aptamers optimizing in vitro selection steps with phosphorothioate nucleotides.HAPIscreen, a method for high-throughput aptamer identification.Regulating eukaryotic gene expression with aptamers.SELEX and dynamic combinatorial chemistry interplay for the selection of conjugated RNA aptamers.In vitro selection of RNA aptamers derived from a genomic human library against the TAR RNA element of HIV-1.Aptamers: a new class of oligonucleotides in the drug discovery pipeline?Surface plasmon resonance investigation of RNA aptamer-RNA ligand interactions.Loop-loop interaction of HIV-1 TAR RNA with N3'-->P5' deoxyphosphoramidate aptamers inhibits in vitro Tat-mediated transcriptionAntimessenger oligodeoxyribonucleotides: an alternative to antisense RNA for artificial regulation of gene expression--a review.Aptamer-mediated nanoparticle interactions: from oligonucleotide-protein complexes to SELEX screens.Antisense phosphorothioate oligonucleotides: selective killing of the intracellular parasite Leishmania amazonensis.LNA derivatives of a kissing aptamer targeted to the trans-activating responsive RNA element of HIV-1.Aptamers as imaging agents.Aptamer selection by direct microfluidic recovery and surface plasmon resonance evaluation.Comparative studies of tricyclo-DNA- and LNA-containing oligonucleotides as inhibitors of HIV-1 gene expression.Single-molecule observations of RNA-RNA kissing interactions in a DNA nanostructure.An improved design of the kissing complex-based aptasensor for the detection of adenosine.Riboswitches based on kissing complexes for the detection of small ligands.Binding of oligopyrimidines to the RNA hairpin responsible for the ribosome gag-pol frameshift in HIV-1.Benzoquinazoline derivatives as substitutes for thymine in nucleic acid complexes. Use of fluorescence emission of benzo[g]quinazoline-2,4-(1H,3H)-dione in probing duplex and triplex formation.Selective inhibition of cell-free translation by oligonucleotides targeted to a mRNA hairpin structure.An acridine-linked oligodeoxynucleotide targeted to the common 5' end of trypanosome mRNAs kills cultured parasites.The common 5' terminal sequence on trypanosome mRNAs: a target for anti-messenger oligodeoxynucleotides.LNA/DNA chimeric oligomers mimic RNA aptamers targeted to the TAR RNA element of HIV-1.Mapping of a minimal AU-rich sequence required for lipopolysaccharide-induced binding of a 55-kDa protein on tumor necrosis factor-alpha mRNA.Interaction of a tryptophan-containing peptide with chromatin core particles. A fluorescence study.New ways of initiating translation in eukaryotes.A boost for the emerging field of RNA nanotechnologyDeterminants of apical loop-internal loop RNA-RNA interactions involving the HCV IRES.Apical loop-internal loop interactions: a new RNA-RNA recognition motif identified through in vitro selection against RNA hairpins of the hepatitis C virus mRNA.Use of dynamic combinatorial chemistry for the identification of covalently appended residues that stabilize oligonucleotide complexes.Hexitol nucleic acid-containing aptamers are efficient ligands of HIV-1 TAR RNA.Electrostatics Explains the Position-Dependent Effect of G⋅U Wobble Base Pairs on the Affinity of RNA Kissing Complexes.
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Jean-Jacques Toulmé
@ast
Jean-Jacques Toulmé
@en
Jean-Jacques Toulmé
@es
Jean-Jacques Toulmé
@nl
type
label
Jean-Jacques Toulmé
@ast
Jean-Jacques Toulmé
@en
Jean-Jacques Toulmé
@es
Jean-Jacques Toulmé
@nl
prefLabel
Jean-Jacques Toulmé
@ast
Jean-Jacques Toulmé
@en
Jean-Jacques Toulmé
@es
Jean-Jacques Toulmé
@nl
P106
P1153
7005630654
P31
P496
0000-0002-8432-5034