about
Discovery of a Novel Class of Covalent Inhibitor for Aldehyde DehydrogenasesStructural basis for 2'-phosphate incorporation into glycogen by glycogen synthaseMolecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulationA systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300.Discovery and characterization of small molecules that target the GTPase RalTarget-specific support vector machine scoring in structure-based virtual screening: computational validation, in vitro testing in kinases, and effects on lung cancer cell proliferationRelative inhibitory potency of molinate and metabolites with aldehyde dehydrogenase 2: implications for the mechanism of enzyme inhibitionSuppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complexVirtual screening targeting the urokinase receptor, biochemical and cell-based studies, synthesis, pharmacokinetic characterization, and effect on breast tumor metastasisDesign, synthesis, biochemical studies, cellular characterization, and structure-based computational studies of small molecules targeting the urokinase receptor.Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides.A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors.Synthesis of a 3-methyluridine phosphoramidite to investigate the role of methylation in a ribosomal RNA hairpin.A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function.Chemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1.7 channelsMolecular biology: RNA in controlA Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B).NMR studies of protein-RNA interactions(-)-Hardwickiic Acid and Hautriwaic Acid Induce Antinociception via Blockade of Tetrodotoxin-Sensitive Voltage-Dependent Sodium ChannelsEvaluation of edonerpic maleate as a CRMP2 inhibitor for pain reliefThe Natural Flavonoid Naringenin Elicits Analgesia through Inhibition of NaV1.8 Voltage-Gated Sodium Channels1H, 15N and 13C backbone assignment of apo TDP-43 RNA recognition motifsDiscovery and Characterization of 2,5-Substituted Benzoic Acid Dual Inhibitors of the Anti-apoptotic Mcl-1 and Bfl-1 ProteinsSmall Molecule Targeting TDP-43's RNA Recognition Motifs Reduces Locomotor Defects in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS)
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
May Khanna
@ast
May Khanna
@en
May Khanna
@es
May Khanna
@nl
type
label
May Khanna
@ast
May Khanna
@en
May Khanna
@es
May Khanna
@nl
prefLabel
May Khanna
@ast
May Khanna
@en
May Khanna
@es
May Khanna
@nl
P106
P31
P496
0000-0002-9989-6374