about
Elucidating the exact role of engineered CRABPII residues for the formation of a retinal protonated Schiff baseTuning the Electronic Absorption of Protein-Embedded All-trans-RetinalRational Design of a Colorimetric pH Sensor from a Soluble Retinoic Acid ChaperoneOptimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacyMethod for Sorting and Pairwise Selection of Nanobodies for the Development of Highly Sensitive Sandwich ImmunoassaysSymmetric adamantyl-diureas as soluble epoxide hydrolase inhibitors.Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission.An omega-3 epoxide of docosahexaenoic acid lowers blood pressure in angiotensin-II-dependent hypertension.Identification of potent inhibitors of the chicken soluble epoxide hydrolase."Turn-on" protein fluorescence: in situ formation of cyanine dyesEpoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures.PPARδ signaling mediates the cytotoxicity of DHA in H9c2 cells.Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain.Cytochrome P450 Oxidase 2C Inhibition Adds to ω-3 Long-Chain Polyunsaturated Fatty Acids Protection Against Retinal and Choroidal Neovascularization.Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3- (1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice.Unique mechanistic insights into the beneficial effects of soluble epoxide hydrolase inhibitors in the prevention of cardiac fibrosis.Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis.Förster resonance energy transfer competitive displacement assay for human soluble epoxide hydrolase.Pro-atherogenic role of smooth muscle Nox4-based NADPH oxidase.Soluble Epoxide Hydrolase Inhibition and Epoxyeicosatrienoic Acid Treatment Improve Vascularization of Engineered Skin SubstitutesDissection of the critical binding determinants of cellular retinoic acid binding protein II by mutagenesis and fluorescence binding assay.Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia.Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.Ingestion of the epoxide hydrolase inhibitor AUDA modulates immune responses of the mosquito, Culex quinquefasciatus during blood feeding.Soluble Epoxide Hydrolase Pharmacological Inhibition Decreases Alveolar Bone Loss by Modulating Host Inflammatory Response, RANK-Related Signaling, Endoplasmic Reticulum Stress, and Apoptosis.Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis.Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation.Cyclooxygenase-derived proangiogenic metabolites of epoxyeicosatrienoic acids.Chemical synthesis and biological evaluation of ω-hydroxy polyunsaturated fatty acids.Inhibition of soluble epoxide hydrolase augments astrocyte release of vascular endothelial growth factor and neuronal recovery after oxygen-glucose deprivation.Synthesis of cyclooxygenase metabolites of 8,9-epoxyeicosatrienoic acid (EET): 11- and 15-hydroxy 8,9-EETs.A new sensitive LC/MS/MS analysis of vitamin D metabolites using a click derivatization reagent, 2-nitrosopyridine.Epoxide metabolites of arachidonate and docosahexaenoate function conversely in acute kidney injury involved in GSK3β signaling.Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase.Probing the orientation of inhibitor and epoxy-eicosatrienoic acid binding in the active site of soluble epoxide hydrolase.ω-3 Polyunsaturated fatty acids and their cytochrome P450-derived metabolites suppress colorectal tumor development in mice.Soluble Epoxide Hydrolase Inhibitor Attenuates Lipopolysaccharide-Induced Acute Lung Injury and Improves Survival in Mice.Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization.Epoxy fatty acids mediate analgesia in murine diabetic neuropathy.Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia.
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Kin Sing Stephen Lee
@ast
Kin Sing Stephen Lee
@en
Kin Sing Stephen Lee
@es
Kin Sing Stephen Lee
@nl
type
label
Kin Sing Stephen Lee
@ast
Kin Sing Stephen Lee
@en
Kin Sing Stephen Lee
@es
Kin Sing Stephen Lee
@nl
prefLabel
Kin Sing Stephen Lee
@ast
Kin Sing Stephen Lee
@en
Kin Sing Stephen Lee
@es
Kin Sing Stephen Lee
@nl
P106
P31
P496
0000-0003-4541-3063