Activation of ADP-ribosylation factor regulates biogenesis of the ATP7A-containing trans-Golgi network compartment and its Cu-induced trafficking
about
The Sec7 guanine nucleotide exchange factor GBF1 regulates membrane recruitment of BIG1 and BIG2 guanine nucleotide exchange factors to the trans-Golgi network (TGN)Transport of mannose-6-phosphate receptors from the trans-Golgi network to endosomes requires Rab31ATP7A trafficking and mechanisms underlying the distal motor neuropathy induced by mutations in ATP7A.Haploinsufficiency of the Sec7 guanine nucleotide exchange factor gea1 impairs septation in fission yeast.The Garz Sec7 domain guanine nucleotide exchange factor for Arf regulates salivary gland development in DrosophilaDirect interactions of adaptor protein complexes 1 and 2 with the copper transporter ATP7A mediate its anterograde and retrograde traffickingSec61β controls sensitivity to platinum-containing chemotherapeutic agents through modulation of the copper-transporting ATPase ATP7AGolgicide A reveals essential roles for GBF1 in Golgi assembly and functionTrafficking of the Menkes copper transporter ATP7A is regulated by clathrin-, AP-2-, AP-1-, and Rab22-dependent stepsHuman copper transporters: mechanism, role in human diseases and therapeutic potential.Cargo loading at the ER.Advances in the understanding of mammalian copper transporters.Golgi in copper homeostasis: a view from the membrane trafficking field.Identification of a functional domain within the p115 tethering factor that is required for Golgi ribbon assembly and membrane trafficking.Characterizing the molecular phenotype of an Atp7a(T985I) conditional knock in mouse model for X-linked distal hereditary motor neuropathy (dHMNX).Organ-specific regulation of ATP7A abundance is coordinated with systemic copper homeostasis.
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P2860
Activation of ADP-ribosylation factor regulates biogenesis of the ATP7A-containing trans-Golgi network compartment and its Cu-induced trafficking
description
article
@en
im Dezember 2007 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в грудні 2007
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name
Activation of ADP-ribosylation ...... and its Cu-induced trafficking
@en
Activation of ADP-ribosylation ...... and its Cu-induced trafficking
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type
label
Activation of ADP-ribosylation ...... and its Cu-induced trafficking
@en
Activation of ADP-ribosylation ...... and its Cu-induced trafficking
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prefLabel
Activation of ADP-ribosylation ...... and its Cu-induced trafficking
@en
Activation of ADP-ribosylation ...... and its Cu-induced trafficking
@nl
P2093
P2860
P1476
Activation of ADP-ribosylation ...... and its Cu-induced trafficking
@en
P2093
Elizabeth Sztul
Julie A. Coventry
Melanie L. Styers
Robert Grabski
Tomasz Szul
Zoe G. Holloway
P2860
P304
C1753-C1767
P356
10.1152/AJPCELL.00253.2007
P577
2007-12-01T00:00:00Z