Blood malignancies presenting with mutations at equivalent residues in RUNX1–2 suggest a common leukemogenic pathway

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Blood malignancies presenting with mutations at equivalent residues in RUNX1–2 suggest a common leukemogenic pathway

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http://www.wikidata.org/entity/Q57587996

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im Januar 2017 veröffentlichter wissenschaftlicher Artikel

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wetenschappelijk artikel

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наукова стаття, опублікована в січні 2017

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Blood malignancies presenting ...... a common leukemogenic pathway

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Blood malignancies presenting ...... a common leukemogenic pathway

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Blood malignancies presenting ...... a common leukemogenic pathway

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Blood malignancies presenting ...... a common leukemogenic pathway

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Blood malignancies presenting ...... a common leukemogenic pathway

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Blood malignancies presenting ...... a common leukemogenic pathway

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P1476

Blood malignancies presenting ...... a common leukemogenic pathway

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P2093

Emanuele Bellacchio

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Francesco Callea

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Francisco Cammarata-Scalisi

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Michele Callea

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P2860

Subcellular localization of the alpha and beta subunits of the acute myeloid leukemia-linked transcription factor PEBP2/CBF

The RUNX genes: gain or loss of function in cancer

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia.

In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms of pathogenesis.

Mutation analysis of core binding factor A1 in patients with cleidocranial dysplasia.

The protooncogene product, PEBP2beta/CBFbeta, is mainly located in the cytoplasm and has an affinity with cytoskeletal structures.

Point mutations in the RUNX1/AML1 gene: another actor in RUNX leukemia.

MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma.

Cbfb deficiency results in differentiation blocks and stem/progenitor cell expansion in hematopoiesis.

Acute myeloid leukemia in a 3 years old child with cleidocranial dysplasia

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2002-2004

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scholarly article

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10.1080/10428194.2016.1274980

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P433

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P478

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Enrico Bertini

Fabiana Fattori

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2017-01-16T00:00:00Z

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28093006

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