ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model
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Pathological and protective roles of glia in chronic painSciatic nerve ligation-induced proliferation of spinal cord astrocytes is mediated by kappa opioid activation of p38 mitogen-activated protein kinaseImpaired inflammatory pain and thermal hyperalgesia in mice expressing neuron-specific dominant negative mitogen activated protein kinase kinase (MEK)Non-invasive Brain Stimulation, a Tool to Revert Maladaptive Plasticity in Neuropathic PainMicroglia in the spinal cord and neuropathic painMicroglia and spinal cord synaptic plasticity in persistent painThe glutamatergic system as a target for neuropathic pain reliefGlial contributions to visceral pain: implications for disease etiology and the female predominance of persistent painNeurotrophins and Neuropathic Pain: Role in PathobiologyEmerging targets in neuroinflammation-driven chronic painAnti-allodynic effect of Buja in a rat model of oxaliplatin-induced peripheral neuropathy via spinal astrocytes and pro-inflammatory cytokines suppressionTramadol and propentofylline coadministration exerted synergistic effects on rat spinal nerve ligation-induced neuropathic painARA 290, a peptide derived from the tertiary structure of erythropoietin, produces long-term relief of neuropathic pain coupled with suppression of the spinal microglia responseActivation of the neuronal extracellular signal-regulated kinase 2 in the spinal cord dorsal horn is required for complete Freund's adjuvant-induced pain hypersensitivityMAP kinase and pain.Activation of extracellular signal-regulated kinase in the anterior cingulate cortex contributes to the induction and expression of affective pain.Genetic targeting of ERK1 suggests a predominant role for ERK2 in murine pain modelsEndosome-mediated retrograde axonal transport of P2X3 receptor signals in primary sensory neuronsThe Qualitative Hyperalgesia Profile: A New Metric to Assess Chronic Post-Thoracotomy Pain.Ketamine does not produce relief of neuropathic pain in mice lacking the β-common receptor (CD131).Crosstalk between spinal astrocytes and neurons in nerve injury-induced neuropathic pain.Suppression of spinal connexin 43 expression attenuates mechanical hypersensitivity in rats after an L5 spinal nerve injury.Microglial TNFα Induces COX2 and PGI2 Synthase Expression in Spinal Endothelial Cells during Neuropathic Pain.T-cell infiltration and signaling in the adult dorsal spinal cord is a major contributor to neuropathic pain-like hypersensitivity.The c-Jun N-terminal kinase 1 (JNK1) in spinal astrocytes is required for the maintenance of bilateral mechanical allodynia under a persistent inflammatory pain conditionChronic tooth pulp inflammation induces persistent expression of phosphorylated ERK (pERK) and phosphorylated p38 (pp38) in trigeminal subnucleus caudalis.Targeting the Microglial Signaling Pathways: New Insights in the Modulation of Neuropathic Pain.Neuregulin-ErbB signaling promotes microglial proliferation and chemotaxis contributing to microgliosis and pain after peripheral nerve injury.Spinal inhibition of p38 MAP kinase reduces inflammatory and neuropathic pain in male but not female mice: Sex-dependent microglial signaling in the spinal cord.[EXPRESS] CXCL12/CXCR4 signaling mediated ERK1/2 activation in spinal cord contributes to the pathogenesis of postsurgical pain in rats.Flexibilide obtained from cultured soft coral has anti-neuroinflammatory and analgesic effects through the upregulation of spinal transforming growth factor-β1 in neuropathic ratsMorphine tolerance attenuates the resolution of postoperative pain and enhances spinal microglial p38 and extracellular receptor kinase phosphorylation.The astrocyte-targeted therapy by Bushi for the neuropathic pain in mice.Prolonged nociceptive responses to hind paw formalin injection in rats with a spinal cord injuryNeuropathic pain model of peripheral neuropathies mediated by mutations of glycyl-tRNA synthetaseAdditive antinociceptive effects of a combination of vitamin C and vitamin E after peripheral nerve injury.Combining ketamine with astrocytic inhibitor as a potential analgesic strategy for neuropathic pain ketamine, astrocytic inhibitor and pain.Pretreatment with intrathecal amitriptyline potentiates anti-hyperalgesic effects of post-injury intra-peritoneal amitriptyline following spinal nerve ligationInvolvement of AMPA receptor GluR2 and GluR3 trafficking in trigeminal spinal subnucleus caudalis and C1/C2 neurons in acute-facial inflammatory pain.Contribution of Primary Afferent Input to Trigeminal Astroglial Hyperactivity, Cytokine Induction and NMDA Receptor Phosphorylation.
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ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model
description
article
@en
im März 2005 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в березні 2005
@uk
name
ERK is sequentially activated ...... in this neuropathic pain model
@en
ERK is sequentially activated ...... in this neuropathic pain model
@nl
type
label
ERK is sequentially activated ...... in this neuropathic pain model
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ERK is sequentially activated ...... in this neuropathic pain model
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prefLabel
ERK is sequentially activated ...... in this neuropathic pain model
@en
ERK is sequentially activated ...... in this neuropathic pain model
@nl
P2093
P921
P1433
P1476
ERK is sequentially activated ...... in this neuropathic pain model
@en
P2093
Clifford J. Woolf
Peter Gerner
Zhi-Ye Zhuang
P304
P356
10.1016/J.PAIN.2004.12.022
P407
P50
P577
2005-03-01T00:00:00Z