about
A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.Enhancing the genome editing toolbox: genome wide CRISPR arrayed librariesHemopoietic-specific Sf3b1-K700E knock-in mice display the splicing defect seen in human MDS but develop anemia without ring sideroblasts.Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia.Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control.Glutaminolysis is a metabolic dependency in FLT3ITD acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition.Effect of BRCA1 immunohistochemical localizations on prognosis of patients with sporadic breast carcinomas.UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programsSRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethalityDissecting the early steps of MLL induced leukaemogenic transformation using a mouse model of AML
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Q34543038-055743B1-C3B4-4C13-B15F-6CB950BC700FQ36378294-53C3724E-EBE4-4BCB-8FAF-FCFD1ED70BADQ38376585-34DA875C-646E-4EF0-8E2D-F8CC4C809EEBQ38429500-59436EA3-30FB-482D-B583-BCC2BFA01325Q47352505-85031F72-B4B7-4426-9C23-730F53C9F8F3Q49791801-18D86C06-9A74-459B-A2F4-90C2C1FCA7E5Q54343471-1C460E00-0578-448B-8151-E0C964A4D325Q56968690-E2C23BA6-57B0-4B07-BB25-AEFB95BD3B8DQ60300790-BC38861E-05A6-4670-B43A-5B54C98E8E8CQ63965509-93B1C946-0DD6-49D4-AB58-855F112160D6Q90371841-252C3939-1875-4C74-B054-079042E67FCE
P50
description
onderzoeker
@nl
researcher, ORCID id # 0000-0002-4865-7648
@en
name
Konstantinos Tzelepis
@ast
Konstantinos Tzelepis
@en
Konstantinos Tzelepis
@es
Konstantinos Tzelepis
@nl
type
label
Konstantinos Tzelepis
@ast
Konstantinos Tzelepis
@en
Konstantinos Tzelepis
@es
Konstantinos Tzelepis
@nl
prefLabel
Konstantinos Tzelepis
@ast
Konstantinos Tzelepis
@en
Konstantinos Tzelepis
@es
Konstantinos Tzelepis
@nl
P106
P31
P496
0000-0002-4865-7648