about
Molecular integrative clustering of Asian gastric cell lines revealed two distinct chemosensitivity clustersFZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway.A central role for TRPS1 in the control of cell cycle and cancer development.Utilization of the Eμ-Myc mouse to model heterogeneity of therapeutic response.Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients.EMT-induced stemness and tumorigenicity are fueled by the EGFR/Ras pathway.An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530).Manganese superoxide dismutase is a promising target for enhancing chemosensitivity of basal-like breast carcinoma.Phosphatase of regenerating liver-3 is regulated by signal transducer and activator of transcription 3 in acute myeloid leukemia.Targeting WNT1-inducible signaling pathway protein 2 alters human breast cancer cell susceptibility to specific lysis through regulation of KLF-4 and miR-7 expression.Epithelial-mesenchymal status renders differential responses to cisplatin in ovarian cancer.Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell-mediated lysis.Raf kinase inhibitory protein role in the molecular subtyping of breast cancer.Dual role of autophagy in hallmarks of cancer.Detection of aneuploidy from single fetal nucleated red blood cells using whole genome sequencing.Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects.Non-invasive prenatal diagnostic testing for β-thalassaemia using cell-free fetal DNA and next generation sequencing.Non-canonical activation of β-catenin by PRL-3 phosphatase in acute myeloid leukemiaDecoding transcriptomic intra-tumour heterogeneity to guide personalised medicine in ovarian cancerBromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcomaSNAI1 recruits HDAC1 to suppress SNAI2 transcription during epithelial to mesenchymal transition.The tumour suppressor OPCML promotes AXL inactivation by the phosphatase PTPRG in ovarian cancerc-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progressionInflammatory and mitogenic signals drive interleukin 23 subunit alpha (IL23A) secretion independent of IL12B in intestinal epithelial cellsA common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinomaAuthor Correction: c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progressionPharmacological Inhibition of TFF3 Enhances Sensitivity of CMS4 Colorectal Carcinoma to 5-Fluorouracil through Inhibition of p44/42 MAPKThe role of GRHL2 and epigenetic remodeling in epithelial-mesenchymal plasticity in ovarian cancer cellsUSP26 regulates TGF-β signaling by deubiquitinating and stabilizing SMAD7Integrative Analysis and Machine Learning based Characterization of Single Circulating Tumor CellsTargeting codon 158 p53-mutant cancers via the induction of p53 acetylationSNAI1-Driven Sequential EMT Changes Attributed by Selective Chromatin Enrichment of RAD21 and GRHL2Development and validation of the gene-expression Predictor of high-grade-serous Ovarian carcinoma molecular subTYPE (PrOTYPE)
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P50
description
researcher, ORCID id # 0000-0001-6624-1593
@en
wetenschapper
@nl
name
Tuan Zea Tan
@ast
Tuan Zea Tan
@en
Tuan Zea Tan
@es
Tuan Zea Tan
@nl
type
label
Tuan Zea Tan
@ast
Tuan Zea Tan
@en
Tuan Zea Tan
@es
Tuan Zea Tan
@nl
prefLabel
Tuan Zea Tan
@ast
Tuan Zea Tan
@en
Tuan Zea Tan
@es
Tuan Zea Tan
@nl
P106
P31
P496
0000-0001-6624-1593