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The 2 Å crystal structure of leucyl-tRNA synthetase and its complex with a leucyl-adenylate analogueClass I tyrosyl-tRNA synthetase has a class II mode of cognate tRNA recognitionStructural and mechanistic basis of pre- and posttransfer editing by leucyl-tRNA synthetaseStructural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansionRefined crystal structure of the seryl-tRNA synthetase from Thermus thermophilus at 2.5 A resolutionLeucyl-tRNA synthetase-dependent and -independent activation of a group I intronDiscovery of potent anti-tuberculosis agents targeting leucyl-tRNA synthetase.Mammalian translation elongation factor eEF1A2: X-ray structure and new features of GDP/GTP exchange mechanism in higher eukaryotes.Purification, crystallization and preliminary X-ray crystallographic analysis of mammalian translation elongation factor eEF1A2.The crystal structure of leucyl-tRNA synthetase complexed with tRNALeu in the post-transfer-editing conformation.Molecular modeling and molecular dynamics simulation study of archaeal leucyl-tRNA synthetase in complex with different mischarged tRNA in editing conformation.Identification of Mycobacterium tuberculosis leucyl-tRNA synthetase (LeuRS) inhibitors among the derivatives of 5-phenylamino-2H-[1,2,4]triazin-3-one.Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing DomainCrystallization and preliminary crystallographic analysis ofThermus thermophilusleucyl-tRNA synthetase and its complexes with leucine and a non-hydrolysable leucyl-adenylate analogueCrystallization and preliminary X-ray diffraction analysis ofThermus thermophilusprolyl-tRNA synthetaseImproved crystals ofThermus thermophilusprolyl-tRNA synthetase complexed with cognate tRNA obtained by crystallization from precipitateCrystallization ofThermus thermophilus histidyl-tRNA synthetase and Its complex with tRNAHisThe structural basis for seryl-adenylate and Ap4A synthesis by seryl-tRNA synthetaseCocrystallization of Lysyl-tRNA synthetase fromThermus thermophilus with its cognate tRNAlys and withEscherichia coli tRNAlysA new crystal form of the complex between seryl-tRNA synthetase and tRNA(Ser) from Thermus thermophilus that diffracts to 2.8 A resolutionCrystallization of the seryl-tRNA synthetase-tRNA(Ser) complex from Thermus thermophilusA new mechanism of post-transfer editing by aminoacyl-tRNA synthetases: catalysis of hydrolytic reaction by bacterial-type prolyl-tRNA synthetaseA molecular dynamics simulation study of amino acid selectivity of LeuRS editing domain from Thermus thermophilusThe Dual Role of the 2'-OH Group of A76 tRNATyr in the Prevention of d-tyrosine MistranslationSubstrate-assisted mechanism of catalytic hydrolysis of misaminoacylated tRNA required for protein synthesis fidelity
P50
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P50
description
researcher, ORCID id # 0000-0002-0982-2372
@en
wetenschapper
@nl
name
Michael Tukalo
@ast
Michael Tukalo
@en
Michael Tukalo
@es
Michael Tukalo
@nl
type
label
Michael Tukalo
@ast
Michael Tukalo
@en
Michael Tukalo
@es
Michael Tukalo
@nl
prefLabel
Michael Tukalo
@ast
Michael Tukalo
@en
Michael Tukalo
@es
Michael Tukalo
@nl
P106
P1153
7004077181
P31
P496
0000-0002-0982-2372