Definition of a Composite Binding Site for gp130 in Human Interleukin-6
about
Identification of three distinct receptor binding sites of murine interleukin-11Interleukin-11 signals through the formation of a hexameric receptor complexFunction and molecular modeling of the interaction between human interleukin 6 and its HNK-1 oligosaccharide ligandsReceptor recognition sites of cytokines are organized as exchangeable modules. Transfer of the leukemia inhibitory factor receptor-binding site from ciliary neurotrophic factor to interleukin-6.Selective enhancement of thrombopoietic activity of PEGylated interleukin 6 by a simple procedure using a reversible amino-protective reagent.A ligand peptide motif selected from a cancer patient is a receptor-interacting site within human interleukin-11.Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130.Leukemia inhibitory factor (LIF), cardiotrophin-1, and oncostatin M share structural binding determinants in the immunoglobulin-like domain of LIF receptor.Interaction of granulocyte colony-stimulating factor (G-CSF) with its receptor. Evidence that Glu19 of G-CSF interacts with Arg288 of the receptor.Analysis of the mechanism of action of anti-human interleukin-6 and anti-human interleukin-6 receptor-neutralising monoclonal antibodies.A Kaposi's sarcoma-associated herpesvirus-encoded cytokine homolog (vIL-6) activates signaling through the shared gp130 receptor subunit.Identification of residues in the putative 5th helical region of human interleukin-6, important for activation of the IL-6 signal transducer, gp130.
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P2860
Definition of a Composite Binding Site for gp130 in Human Interleukin-6
description
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
im Dezember 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Journal of Biological Chemistry
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в грудні 1995
@uk
name
Definition of a Composite Binding Site for gp130 in Human Interleukin-6
@en
Definition of a Composite Binding Site for gp130 in Human Interleukin-6
@nl
type
label
Definition of a Composite Binding Site for gp130 in Human Interleukin-6
@en
Definition of a Composite Binding Site for gp130 in Human Interleukin-6
@nl
prefLabel
Definition of a Composite Binding Site for gp130 in Human Interleukin-6
@en
Definition of a Composite Binding Site for gp130 in Human Interleukin-6
@nl
P2093
P2860
P50
P356
P1476
Definition of a composite binding site for gp130 in human interleukin-6
@en
P2093
P2860
P304
31249-31254
P356
10.1074/JBC.270.52.31249
P407
P577
1995-12-01T00:00:00Z