Systemic network analysis identifies XIAP and IκBα as potential drug targets in TRAIL resistant BRAF mutated melanoma

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Systemic network analysis identifies XIAP and IκBα as potential drug targets in TRAIL resistant BRAF mutated melanoma

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scientific article published on 05 November 2018

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wetenschappelijk artikel

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наукова стаття, опублікована у 2018

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Systemic network analysis iden ...... esistant BRAF mutated melanoma

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Systemic network analysis iden ...... esistant BRAF mutated melanoma

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Systemic network analysis iden ...... esistant BRAF mutated melanoma

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Systemic network analysis iden ...... esistant BRAF mutated melanoma

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Systemic network analysis iden ...... esistant BRAF mutated melanoma

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Systemic network analysis iden ...... esistant BRAF mutated melanoma

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P1476

Systemic network analysis iden ...... esistant BRAF mutated melanoma

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Anna Zinoveva

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Dagmar Kulms

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Greta Del Mistro

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Ines Müller

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Martin Siegemund

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Meike Hutt

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Roland E Kontermann

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Stefan Beissert

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Sébastien De Landtsheer

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Thomas Sauter

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P2860

Tunable-combinatorial mechanisms of acquired resistance limit the efficacy of BRAF/MEK cotargeting but result in melanoma drug addiction.

Three-dimensional cell culture systems and their applications in drug discovery and cell-based biosensors

Treatment of NRAS-mutated advanced or metastatic melanoma: rationale, current trials and evidence to date

Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib

The immune microenvironment confers resistance to MAPK pathway inhibitors through macrophage-derived TNFα

optPBN: an optimisation toolbox for probabilistic Boolean networks.

Three-dimensional cell culture: a breakthrough in vivo.

NF-κB Regulation of c-FLIP Promotes TNFα-Mediated RAF Inhibitor Resistance in Melanoma

High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancer.

On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeutics.

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s41540-018-0075-y

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scholarly article

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10.1038/S41540-018-0075-Y

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English

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Philippe Lucarelli

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2018-11-05T00:00:00Z

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1107912933

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30416750

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6218484

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