Autophagy induces transforming growth factor-β-dependent epithelial-mesenchymal transition in hepatocarcinoma cells through cAMP response element binding signalling

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Autophagy induces transforming growth factor-β-dependent epithelial-mesenchymal transition in hepatocarcinoma cells through cAMP response element binding signalling

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im November 2018 veröffentlichter wissenschaftlicher Artikel

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scientific article published on 22 August 2018

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wetenschappelijk artikel

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наукова стаття, опублікована в листопаді 2018

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Autophagy induces transforming ...... nse element binding signalling

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Autophagy induces transforming ...... nse element binding signalling

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Autophagy induces transforming ...... nse element binding signalling

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Autophagy induces transforming ...... nse element binding signalling

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Autophagy induces transforming ...... nse element binding signalling

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Autophagy induces transforming ...... nse element binding signalling

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P1476

Autophagy induces transforming ...... nse element binding signalling

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P2093

Jing Yang

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Liyu Wang

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Shaobo Hu

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Xi Zhang

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Yongzhong Wu

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Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis

Requirement of Smad3 and CREB-1 in mediating transforming growth factor-beta (TGF beta) induction of TGF beta 3 secretion

Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis

TGF-beta-induced epithelial to mesenchymal transition

Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP).

Activation of cAMP-responsive-element-binding protein by PI3 kinase and p38 MAPK is essential for elevated expression of transforming growth factor β2 in cancer cells.

What turns CREB on?

Autophagy: regulation and role in development

Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of cancer.

Treatment options in hepatocellular carcinoma today.

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5518-5532

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scholarly article

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10.1111/JCMM.13825

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English

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Jun Li

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2018-08-22T00:00:00Z

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30134011

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molecular medicine

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6201351

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